Endothelial function in cardiovascular medicine: a consensus paper of the European society of cardiology working groups on atherosclerosis and vascular biology …

Y Alexander, E Osto, A Schmidt-Trucksäss… - Cardiovascular …, 2021 - academic.oup.com
Endothelial cells (ECs) are sentinels of cardiovascular health. Their function is reduced by
the presence of cardiovascular risk factors, and is regained once pathological stimuli are …

[HTML][HTML] Retinal vessel diameters and function in cardiovascular risk and disease

H Hanssen, L Streese, W Vilser - Progress in retinal and eye research, 2022 - Elsevier
In the last two decades evidence has gradually accumulated suggesting that the eye may be
a unique window for cardiovascular risk stratification based on the assessment of subclinical …

A foundation model for generalizable disease detection from retinal images

Y Zhou, MA Chia, SK Wagner, MS Ayhan… - Nature, 2023 - nature.com
Medical artificial intelligence (AI) offers great potential for recognizing signs of health
conditions in retinal images and expediting the diagnosis of eye diseases and systemic …

[HTML][HTML] Revisiting pharmacology of oxidative stress and endothelial dysfunction in cardiovascular disease: Evidence for redox-based therapies

A Daiber, S Chlopicki - Free Radical Biology and Medicine, 2020 - Elsevier
According to the latest Global Burden of Disease Study data, non-communicable diseases in
general and cardiovascular disease (CVD) in particular are the leading cause of premature …

Artificial intelligence in retinal imaging for cardiovascular disease prediction: current trends and future directions

DYL Wong, MC Lam, A Ran… - Current Opinion in …, 2022 - journals.lww.com
Artificial intelligence based retinal microvasculature analysis may supplement existing CVD
risk stratification approach. Although technical and socioeconomic challenges remain, we …

Persistent endothelial dysfunction in post-COVID-19 syndrome and its associations with symptom severity and chronic inflammation

T Kuchler, R Günthner, A Ribeiro, R Hausinger… - Angiogenesis, 2023 - Springer
Abstract Background Post-COVID-19 syndrome (PCS) is a lingering disease with ongoing
symptoms such as fatigue and cognitive impairment resulting in a high impact on the daily …

Physical activity and exercise improve retinal microvascular health as a biomarker of cardiovascular risk: a systematic review

L Streese, C Guerini, L Bühlmayer, G Lona, C Hauser… - Atherosclerosis, 2020 - Elsevier
Background and aims Physical activity (PA) and fitness are important modulators of vascular
ageing and may therefore help expand individual health span. We aimed to systematically …

Normative data and standard operating procedures for static and dynamic retinal vessel analysis as biomarker for cardiovascular risk

L Streese, G Lona, J Wagner, R Knaier, A Burri… - Scientific reports, 2021 - nature.com
Retinal vessel phenotype is predictive for cardiovascular outcome. This cross-sectional
population-based study aimed to quantify normative data and standard operating …

Impaired retinal microvascular function predicts long-term adverse events in patients with cardiovascular disease

JD Theuerle, AH Al-Fiadh, FM Amirul Islam… - Cardiovascular …, 2021 - academic.oup.com
Aims Endothelial dysfunction is a precursor to the development of symptomatic
atherosclerosis. Retinal microvascular reactivity to flicker light stimulation is a marker of …

Predicting systemic health features from retinal fundus images using transfer-learning-based artificial intelligence models

NC Khan, C Perera, ER Dow, KM Chen, VB Mahajan… - Diagnostics, 2022 - mdpi.com
While color fundus photos are used in routine clinical practice to diagnose ophthalmic
conditions, evidence suggests that ocular imaging contains valuable information regarding …