The role of CD74 in cardiovascular disease

QL Li, J Tang, L Zhao, A Ruze, XF Shan… - Frontiers in …, 2023 - frontiersin.org
Leukocyte differentiation antigen 74 (CD74), also known as invariant chain, is a molecular
chaperone of major histocompatibility complex class II (MHC II) molecules involved in …

Cooperative application of transcriptomics and ceRNA hypothesis: lncRNA-00742/miR-116 targets CD74 to mediate vanadium-induced mitochondrial apoptosis in …

J Chen, X Dai, C Xing, Y Zhang, H Cao, G Hu… - Journal of Hazardous …, 2024 - Elsevier
Vanadium (V) is a poisonous metallic environmental pollutant which poses hazard to the
animal health of the liver. Competitive endogenous ribonucleic acids (ceRNAs) are essential …

Macrophage migration inhibitory factor exerts pro‐proliferative and anti‐apoptotic effects via CD74 in murine hepatocellular carcinoma

TH Wirtz, A Saal, I Bergmann, P Fischer… - British journal of …, 2021 - Wiley Online Library
Background and Purpose Macrophage migration inhibitory factor (MIF) is an inflammatory
and chemokine‐like protein expressed in different inflammatory diseases as well as solid …

Gold nanoparticles attenuate the interferon-γ induced SOCS1 expression and activation of NF-κB p65/50 activity via modulation of microRNA-155-5p in triple-negative …

A Farhana, A Alsrhani, N Rasheed… - Frontiers in …, 2023 - frontiersin.org
Objective Triple-negative breast cancer (TNBC) is a very aggressive form of cancer that
grows and spreads very fast and generally relapses. Therapeutic options of TNBC are …

Tumor necrosis factor α–dependent lung inflammation promotes the progression of lung adenocarcinoma originating from alveolar type II cells by upregulating MIF …

L Cao, X Wang, X Liu, W Meng, W Guo, C Duan… - Laboratory …, 2023 - Elsevier
Lung adenocarcinoma is the most common type of lung cancer. We recently reported that
inflammation-driven lung adenocarcinoma (IDLA) originates from alveolar type (AT)-II cells …

CD74 facilitates immunotherapy response by shaping the tumor microenvironment of hepatocellular carcinoma

J Cheng, J Li, X Jiang, X Ma, B Li, H Zhai, X Luo… - Molecular …, 2024 - Springer
Background CD74 is ectopically expressed in many tumors and can regulate tumor
immunity. However, there are many gaps in the study of the prognostic value of CD74 …

Identification of tumor antigens and immune subtypes in breast cancer for mRNA vaccine development

RQ Li, W Wang, L Yan, LY Song, X Guan… - Frontiers in …, 2022 - frontiersin.org
Background Poor prognosis, resistance to chemotherapy, insensitivity to radiotherapy, and a
high prevalence of adverse drug reactions remain urgent issues for breast cancer (BC) …

[HTML][HTML] A prognostic model related to necrotizing apoptosis of breast cancer based on biorthogonal constrained depth semi-supervised nonnegative matrix …

Y Gao, Q Huang, Y Qin, X Bao, Y Pan… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Breast cancer (BC) is one of the most common malignant tumours in women, and its
prognosis is poor. The prognosis of BC patients can be improved by immunotherapy …

Absence of CD74 isoform at 41kDa prevents the heterotypic associations between CD74 and CD44 in human lung adenocarcinoma-derived cells

W Al Abdulmonem, Z Rasheed… - Immunological …, 2021 - Taylor & Francis
Lung cancer is a leading cause of cancer-associated death in all over the globe. This study
was undertaken to determine the expression and interaction of membrane-bound receptors …

Therapeutic approach for osteoporotic animal model by bone marrow mesenchymal stem cells

ASM Aljohani, AKA Zaki, W Al Abdulmonem… - Journal of Applied …, 2021 - japsonline.com
Osteoporosis (OP) is a common debilitating metabolic bone disorder manifested by poor
mineral density and deteriorated skeleton. Stem cell therapies are being considered as …