Aminoacyl-tRNA synthetases (ARSs) play a vital role in protein synthesis by linking amino
acids to their cognate transfer RNAs (tRNAs). This typical function has been well recognized …

Aminoacyl-tRNA synthetases (aaRSs) catalyze the esterification of tRNA with a cognate
amino acid and are essential enzymes in all three kingdoms of life. Due to their important …

The structural resemblance between the fused imidazopyridine heterocyclic ring system and
purines has prompted biological investigations to assess their potential therapeutic …

The ensemble of aminoacyl tRNA synthetases is regarded as a key component of the
protein translation machinery. With the progressive increase in structure-based studies on …

Aminoacyl-tRNA synthetases (ARSs) are essential enzymes that ligate amino acids to
tRNAs and translate the genetic code during protein synthesis. Their function in pathogen …

Cryptosporidiosis is one of the leading causes of moderate to severe diarrhea in children in
low-resource settings. The therapeutic options for cryptosporidiosis are limited to one drug …

The divergence of fluorine-based systems and significance of their nascent non-covalent
chemistry in molecular assemblies are presented in a brief review of the field. Emphasis has …

Abstract Design, synthesis, and biological evaluation of two series of O 4′-benzyl-hispidol
derivatives and the analogous corresponding O 3′-benzyl derivatives aiming to develop …

Antibiotic-resistant bacteria are widespread and pose a growing threat to human health.
New antibiotics acting by novel mechanisms of action are needed to address this challenge …

A series of new N-substituted pyrazole-containing benzimidazoles was synthesized starting
from 1, 2-diaminobenzene and pyrazole-4-carbaldehyde in good yield. Antioxidant activity of …