Red blood cells (RBCs) exhibit a unique deformability, which enables them to change shape
reversibly in response to an external force. The deformability of RBCs allows them to flow in …

Transfusion Medicine is a dynamically evolving field. Recent high-quality research has
reshaped the paradigms guiding blood transfusion. As increasing evidence supports the …

Background Fresh red cells may improve outcomes in critically ill patients by enhancing
oxygen delivery while minimizing the risks of toxic effects from cellular changes and the …

Background Some observational studies have reported that transfusion of red-cell units that
have been stored for more than 2 to 3 weeks is associated with serious, even fatal, adverse …

Macrophages play important roles in recycling iron derived from the clearance of red blood
cells (RBCs). They are also a critically important component of host defense, protecting …

Time-course investigation of SAGM-stored leukocyte-filtered red bood cell concentrates: from
metabolism to proteomics - PMC Back to Top Skip to main content NIH NLM Logo Access keys …

Permanent availability of red blood cells (RBCs) for transfusion depends on refrigerated
storage, during which morphologically altered RBCs accumulate. Among these, a …

Blood banking underpins modern medical care, but blood storage, necessary for testing and
inventory management, reduces the safety and efficacy of individual units of red blood cells …

Stored red blood cells (RBCs) are needed for life-saving blood transfusions, but they
undergo continuous degradation. RBC storage lesions are often assessed by microscopic …

Hemorrhagic shock is both a local and systemic disorder. In the context of systemic effects,
blood loss may lead to levels of reduced oxygen delivery (DO2) sufficient to cause tissue …