Aging leads to numerous transitions in brain physiology including synaptic dysfunction and
disturbances in cognition and memory. With a few clinically relevant drugs, a substantial …

Modulation of endogenous cellular defense mechanisms represents an innovative approach
to therapeutic intervention in diseases causing chronic tissue damage, such as in …

Ischemic stroke, characterized by the sudden loss of blood flow in specific area (s) of the
brain, is the leading cause of permanent disability and is among the leading causes of death …

Resveratrol, a stilbene formed in many plants in response to various stressors, elicits
multiple beneficial effects in vertebrates. Particularly, resveratrol was shown to have …

Stroke is one of the main causes of mortality and disability, and it is due to be included in
monetary implications on wellbeing frameworks around the world. Ischemic stroke is caused …

Hypoxia is one of the fundamental biological phenomena that are intricately associated with
the development and aggressiveness of a variety of solid tumors. Hypoxia-inducible factors …

Aging, a fundamental physiological process influenced by innumerable biological and
genetic pathways, is an important driving factor for several aging‐associated disorders like …

Resveratrol, a natural stilbene present at relatively high concentrations in grape skin and
seeds and red wine, is known for its purported antioxidant activity in the vascular and …

Mammalian mitochondrial permeability transition pore (MPTP), across the inner and outer
membranes of mitochondria, is a nonspecific channel for signal transduction or material …

Stroke is the second most common cause of death globally and the leading cause of death
in China. The pathogenesis of cerebral ischemia injury is complex, and oxidative stress …