[HTML][HTML] Pharmaceutical strategies to extend pulmonary exposure of inhaled medicines

Y Guo, H Bera, C Shi, L Zhang, D Cun… - Acta Pharmaceutica Sinica …, 2021 - Elsevier
Pulmonary administration route has been extensively exploited for the treatment of local
lung diseases such as asthma, chronic obstructive pulmonary diseases and respiratory …

A review of glycosylated carriers for drug delivery

K Jain, P Kesharwani, U Gupta, NK Jain - Biomaterials, 2012 - Elsevier
Carbohydrates not only represent a vast potential as structure building blocks of living cells
but also have proved as a promising candidate for drug delivery. Glycosylation of …

Pulmonary drug delivery systems for tuberculosis treatment

DD Pham, E Fattal, N Tsapis - International journal of pharmaceutics, 2015 - Elsevier
Tuberculosis (TB) remains a major global health problem as it is the second leading cause
of death from an infectious disease worldwide, after the human immunodeficiency virus …

Nano-and micro-based inhaled drug delivery systems for targeting alveolar macrophages

WH Lee, CY Loo, D Traini… - Expert opinion on drug …, 2015 - Taylor & Francis
Introduction: Macrophages are the most versatile cells in the hematopoietic system and are
strategically distributed in tissues to fight pathogens or other foreign particles. In the lung …

Inhalable solid lipid nanoparticles for intracellular tuberculosis infection therapy: macrophage-targeting and pH-sensitive properties

C Ma, M Wu, W Ye, Z Huang, X Ma, W Wang… - Drug Delivery and …, 2021 - Springer
Mycobacterium tuberculosis (MTB) is one of the most threatening pathogens for its latent
infection in macrophages. The intracellular MTB isolated itself from drugs and could spread …

Mannosylated solid lipid nanoparticles as vectors for site-specific delivery of an anti-cancer drug

A Jain, A Agarwal, S Majumder, N Lariya… - Journal of Controlled …, 2010 - Elsevier
The purpose of the present study was to investigate the tumor targeting potential of surface
tailored solid lipid nanoparticles (SLNs) loaded with an anti-cancer drug doxorubicin HCl …

Inhaled drug therapy for treatment of tuberculosis

A Misra, AJ Hickey, C Rossi, G Borchard, H Terada… - Tuberculosis, 2011 - Elsevier
The lungs have received attention as a portal for drug delivery in tuberculosis (TB) from
researchers addressing diverse objectives. These include:(a) targeting alveolar …

Inhaled drug delivery for tuberculosis therapy

P Muttil, C Wang, AJ Hickey - Pharmaceutical research, 2009 - Springer
One third of the world population is infected with tuberculosis (TB), and new infections occur
at a rate of one per second. The recent increase in the emergence of drug-resistant strains of …

Modulating lung immune cells by pulmonary delivery of antigen-specific nanoparticles to treat autoimmune disease

E Saito, SJ Gurczynski, KR Kramer, CA Wilke… - Science …, 2020 - science.org
Antigen-specific particles can treat autoimmunity, and pulmonary delivery may provide for
easier delivery than intravenous or subcutaneous routes. The lung is a “hub” for …

Nanotherapeutics for pulmonary drug delivery: An emerging approach to overcome respiratory diseases

E Kole, K Jadhav, N Shirsath, P Dudhe… - Journal of Drug Delivery …, 2023 - Elsevier
Pulmonary diseases pose an immense threat to global health. Several nanotherapeutics-
based approaches aimed to tackle pulmonary ailments in recent years. The current …