Insights into the microbial degradation and biochemical mechanisms of carbamates

S Mishra, S Pang, W Zhang, Z Lin, P Bhatt, S Chen - Chemosphere, 2021 - Elsevier
Carbamate compounds are commonly applied in agricultural sectors as alternative options
to the recalcitrant organochlorine pesticides due to their easier breakdown and less …

CYP6 P450 Enzymes and ACE-1 Duplication Produce Extreme and Multiple Insecticide Resistance in the Malaria Mosquito Anopheles gambiae

CV Edi, L Djogbenou, AM Jenkins, K Regna… - PLoS …, 2014 - journals.plos.org
Malaria control relies heavily on pyrethroid insecticides, to which susceptibility is declining in
Anopheles mosquitoes. To combat pyrethroid resistance, application of alternative …

An insecticide resistance-breaking mosquitocide targeting inward rectifier potassium channels in vectors of Zika virus and malaria

DR Swale, DW Engers, SR Bollinger, A Gross… - Scientific reports, 2016 - nature.com
Insecticide resistance is a growing threat to mosquito control programs around the world,
thus creating the need to discover novel target sites and target-specific compounds for …

Vector Control and Insecticidal Resistance in the African Malaria Mosquito Anopheles gambiae

M Schmidt, V Hrabcova, D Jun, K Kuca… - Chemical Research in …, 2018 - ACS Publications
Mosquito-borne diseases (including malaria) belong among the leading causes of death in
humans. Vector control is a crucial part of the global strategy for management of mosquito …

Structure of the G119S mutant acetylcholinesterase of the malaria vector Anopheles gambiae reveals basis of insecticide resistance

J Cheung, A Mahmood, R Kalathur, L Liu, PR Carlier - Structure, 2018 - cell.com
Malaria is a devastating disease in sub-Saharan Africa and is transmitted by the mosquito
Anopheles gambiae. While indoor residual spraying of anticholinesterase insecticides has …

Difluoromethyl ketones: Potent inhibitors of wild type and carbamate-insensitive G119S mutant Anopheles gambiae acetylcholinesterase

E Camerino, DM Wong, F Tong, F Körber… - Bioorganic & medicinal …, 2015 - Elsevier
Malaria is a devastating disease in sub-Saharan Africa, and current vector control measures
are threatened by emerging resistance mechanisms. With the goal of developing new …

Insect acetylcholinesterase as a target for effective and environmentally safe insecticides

YP Pang - advances in insect physiology, 2014 - Elsevier
Insecticides are a cost-effective approach to managing disease-carrying, crop-destroying,
and residential pest insects. However, current anticholinesterase insecticides are toxic to …

Carbamate and pyrethroid resistance in the akron strain of Anopheles gambiae

JM Mutunga, TD Anderson, DT Craft, AD Gross… - Pesticide biochemistry …, 2015 - Elsevier
Insecticide resistance in the malaria vector, Anopheles gambiae, is a serious problem,
epitomized by the multi-resistant Akron strain, originally isolated in the country of Benin …

Acetylcholinesterases from the Disease Vectors Aedes aegypti and Anopheles gambiae: Functional Characterization and Comparisons with Vertebrate Orthologues

C Engdahl, S Knutsson, SÅ Fredriksson, A Linusson… - PLoS …, 2015 - journals.plos.org
Mosquitoes of the Anopheles (An.) and Aedes (Ae.) genus are principal vectors of human
diseases including malaria, dengue and yellow fever. Insecticide-based vector control is an …

Design, synthesis, and evaluation of genistein analogues as anti-cancer agents

P Xiong, R Wang, X Zhang… - Anti-Cancer Agents …, 2015 - ingentaconnect.com
Genistein is a bioactive isoflavone derived from soybeans. The tie-in between the intake of
genistein and the decreased incidence of some solid tumors (including prostate cancer) has …