[HTML][HTML] Lower parathyroid hormone levels are associated with reduced fracture risk in Japanese patients on hemodialysis

H Komaba, T Imaizumi, T Hamano, N Fujii… - Kidney International …, 2024 - Elsevier
Introduction Secondary hyperparathyroidism (SHPT) affects bone metabolism and may lead
to bone fragility. However, there is conflicting evidence as to whether parathyroid hormone …

The Challenge of Fractures in Patients with Chronic Kidney Disease

AG Kattah, SM Titan, RA Wermers - Endocrine Practice, 2024 - Elsevier
People with chronic kidney disease (CKD) are at increased risk of fractures in comparison to
the non-CKD population and fractures are associated with high mortality and worsening …

Multiscale effects of the calcimimetic drug, etelcalcetide on bone health of rats with secondary hyperparathyroidism induced by chronic kidney disease

S Sharma, S Kumar, MS Tomar, D Chauhan… - Bone, 2024 - Elsevier
Chronic kidney disease-induced secondary hyperparathyroidism (CKD-SHPT) heightens
fracture risk through impaired mineral homeostasis and elevated levels of uremic toxins …

Comparative effects of calcitriol and calcimimetic on bone health in renal insufficiency

JM Díaz‐Tocados, ME Rodríguez‐Ortiz… - The FASEB …, 2024 - Wiley Online Library
Calcitriol and calcimimetics are used to treat hyperparathyroidism secondary to chronic
kidney disease (CKD). Calcitriol administration and the subsequent increase in serum …

[HTML][HTML] Rationale and Protocol of the ETERNITY-ITA Study: Use of Etelcalcetide for Preserving Vitamin K-Dependent Protein Activity—An Italian Study

M Fusaro, A Aghi, C Marino, F Mallamaci… - Journal of Clinical …, 2024 - mdpi.com
Background/Objectives: Chronic kidney disease and mineral bone disorders (CKD-MBD)
are frequently associated with an increased risk of both vascular calcifications (VCs) and …

Effectiveness of calcimimetics on fractures in dialysis patients with secondary hyperparathyroidism: meta-analysis of randomized trials

T Wakamatsu, S Yamamoto, K Matsuo… - Journal of Bone and …, 2024 - Springer
Introduction This study aimed to assess the effectiveness of calcimimetics in reducing the
risk of fractures in dialysis patients with secondary hyperparathyroidism (SHPT). Material …

New Insights into the Effects of Etelcalcetide on Bone Health

C Ginsberg, JH Ix - Clinical Journal of the American Society of …, 2023 - journals.lww.com
Calcimimetics are a class of drugs that activate the calcium-sensing receptor leading to
suppression of parathyroid hormone (PTH) production, generally used for the management …

Reducing Elevated Parathyroid Hormone to Protect Bone Strength in End-Stage Kidney Disease

T Isakova, TL Nickolas - … the official journal of the National …, 2024 - pubmed.ncbi.nlm.nih.gov
Reducing Elevated Parathyroid Hormone to Protect Bone Strength in End-Stage Kidney
Disease Reducing Elevated Parathyroid Hormone to Protect Bone Strength in End-Stage …

Effects of Etelcalcetide on Bone Microstructure in the Adenine-Induced Chronic Kidney Disease Rat Model

S Igarashi, Y Kasukawa, K Nozaka… - Open Journal of …, 2023 - asian.go4sending.com
Objective: Chronic kidney disease (CKD) with secondary hyperparathyroidism (SHPT)
increases the risk of fragility fractures with deterioration of cortical and trabecular bone …

Calcium, Phosphate and Bones: How Bone and Mineral Metabolism Is Altered in Kidney Disease

HC Rayner, ME Thomas, I Dasgupta… - Understanding Kidney …, 2025 - Springer
Calcium, Phosphate and Bones: How Bone and Mineral Metabolism Is Altered in Kidney
Disease | SpringerLink Skip to main content Advertisement Springer Nature Link Account Menu …