[HTML][HTML] The predictive coding account of psychosis
Fueled by developments in computational neuroscience, there has been increasing interest
in the underlying neurocomputational mechanisms of psychosis. One successful approach …
in the underlying neurocomputational mechanisms of psychosis. One successful approach …
Autoantibodies to synaptic receptors and neuronal cell surface proteins in autoimmune diseases of the central nervous system
J Dalmau, C Geis, F Graus - Physiological reviews, 2017 - journals.physiology.org
Investigations in the last 10 years have revealed a new category of neurological diseases
mediated by antibodies against cell surface and synaptic proteins. There are currently 16 …
mediated by antibodies against cell surface and synaptic proteins. There are currently 16 …
[HTML][HTML] Changes in global and thalamic brain connectivity in LSD-induced altered states of consciousness are attributable to the 5-HT2A receptor
Background: Lysergic acid diethylamide (LSD) has agonist activity at various serotonin (5-
HT) and dopamine receptors. Despite the therapeutic and scientific interest in LSD, specific …
HT) and dopamine receptors. Despite the therapeutic and scientific interest in LSD, specific …
The neurobiology of depression, ketamine and rapid-acting antidepressants: Is it glutamate inhibition or activation?
The discovery of the antidepressant effects of ketamine has opened a breakthrough
opportunity to develop a truly novel class of safe, effective, and rapid-acting antidepressants …
opportunity to develop a truly novel class of safe, effective, and rapid-acting antidepressants …
[HTML][HTML] Ketamine treatment and global brain connectivity in major depression
Capitalizing on recent advances in resting-state functional connectivity magnetic resonance
imaging (rs-fcMRI) and the distinctive paradigm of rapid mood normalization following …
imaging (rs-fcMRI) and the distinctive paradigm of rapid mood normalization following …
Association of age, antipsychotic medication, and symptom severity in schizophrenia with proton magnetic resonance spectroscopy brain glutamate level: a mega …
Importance Proton magnetic resonance spectroscopy (1H-MRS) studies indicate that altered
brain glutamatergic function may be associated with the pathophysiology of schizophrenia …
brain glutamatergic function may be associated with the pathophysiology of schizophrenia …
The effects of ketamine on prefrontal glutamate neurotransmission in healthy and depressed subjects
The ability of ketamine administration to activate prefrontal glutamate neurotransmission is
thought to be a key mechanism contributing to its transient psychotomimetic effects and its …
thought to be a key mechanism contributing to its transient psychotomimetic effects and its …
Searching for cross-diagnostic convergence: neural mechanisms governing excitation and inhibition balance in schizophrenia and autism spectrum disorders
Recent theoretical accounts have proposed excitation and inhibition (E/I) imbalance as a
possible mechanistic, network-level hypothesis underlying neural and behavioral …
possible mechanistic, network-level hypothesis underlying neural and behavioral …
[HTML][HTML] Ketamine disinhibits dendrites and enhances calcium signals in prefrontal dendritic spines
A subanesthetic dose of ketamine causes acute psychotomimetic symptoms and sustained
antidepressant effects. In prefrontal cortex, the prevailing disinhibition hypothesis posits that …
antidepressant effects. In prefrontal cortex, the prevailing disinhibition hypothesis posits that …
[HTML][HTML] From maps to multi-dimensional network mechanisms of mental disorders
The development of advanced neuroimaging techniques and their deployment in large
cohorts has enabled an assessment of functional and structural brain network architecture at …
cohorts has enabled an assessment of functional and structural brain network architecture at …