Pathogenesis, epidemiology and control of Group A Streptococcus infection

S Brouwer, T Rivera-Hernandez, BF Curren… - Nature Reviews …, 2023 - nature.com
Abstract Streptococcus pyogenes (Group A Streptococcus; GAS) is exquisitely adapted to
the human host, resulting in asymptomatic infection, pharyngitis, pyoderma, scarlet fever or …

COVID-19, myocarditis and pericarditis

DL Fairweather, DJ Beetler, DN Di Florio… - Circulation …, 2023 - Am Heart Assoc
Viral infections are a leading cause of myocarditis and pericarditis worldwide, conditions that
frequently coexist. Myocarditis and pericarditis were some of the early comorbidities …

Circulating spike protein detected in post–COVID-19 mRNA vaccine myocarditis

LM Yonker, Z Swank, YC Bartsch, MD Burns, A Kane… - Circulation, 2023 - Am Heart Assoc
Background: Cases of adolescents and young adults developing myocarditis after
vaccination with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–targeted …

[HTML][HTML] Myocarditis and inflammatory cardiomyopathy: current evidence and future directions

C Tschöpe, E Ammirati, B Bozkurt… - Nature Reviews …, 2021 - nature.com
Inflammatory cardiomyopathy, characterized by inflammatory cell infiltration into the
myocardium and a high risk of deteriorating cardiac function, has a heterogeneous …

COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options

TJ Guzik, SA Mohiddin, A Dimarco, V Patel… - Cardiovascular …, 2020 - academic.oup.com
The novel coronavirus disease (COVID-19) outbreak, caused by SARS-CoV-2, represents
the greatest medical challenge in decades. We provide a comprehensive review of the …

Transforming growth factor-β in myocardial disease

NG Frangogiannis - Nature Reviews Cardiology, 2022 - nature.com
Transforming growth factor-β (TGFβ) isoforms are upregulated and activated in myocardial
diseases and have an important role in cardiac repair and remodelling, regulating the …

Diagnosis and management of myocarditis in children: a scientific statement from the American Heart Association

YM Law, AK Lal, S Chen, D Čiháková, LT Cooper Jr… - Circulation, 2021 - Am Heart Assoc
Myocarditis remains a clinical challenge in pediatrics. Originally, it was recognized at
autopsy before the application of endomyocardial biopsy, which led to a histopathology …

Current challenges and future directions for engineering extracellular vesicles for heart, lung, blood and sleep diseases

G Li, T Chen, J Dahlman… - Journal of …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) carry diverse bioactive components including nucleic acids,
proteins, lipids and metabolites that play versatile roles in intercellular and interorgan …

COVID-19: a case for inhibiting IL-17?

O Pacha, MA Sallman, SE Evans - Nature Reviews Immunology, 2020 - nature.com
IL-17 and IL-17 receptor inhibitors boast an impressive safety history and are widely
available. Here, we argue that targeting IL-17 is immunologically plausible as a strategy to …

T‐cell responses and therapies against SARS‐CoV‐2 infection

SM Toor, R Saleh, V Sasidharan Nair, RZ Taha… - …, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) is caused by SARS‐CoV‐2, a novel
coronavirus strain. Some studies suggest that COVID‐19 could be an immune‐related …