The mononuclear phagocyte system (MPS) is defined as a cell lineage in which committed
marrow progenitors give rise to blood monocytes and tissue macrophages. Here, we discuss …

Ageing is a process that gradually increases the organism's vulnerability to death. It affects
different biological pathways, and the underlying cellular mechanisms are complex. In view …

The role of neutrophils in solid tumor metastasis remains largely controversial. In preclinical
models of solid tumors, both pro-metastatic and anti-metastatic effects of neutrophils have …

Due to differences in human and murine angiotensin converting enzyme 2 (ACE-2) receptor,
initially available SARS-CoV-2 isolates could not infect mice. Here we show that serial …

The migration of polymorphonuclear granulocytes (PMN) into the brain parenchyma and
release of their abundant proteases are considered the main causes of neuronal cell death …

Extended circulation of nanoparticles in blood is essential for most clinical applications.
Nanoparticles are rapidly cleared by cells of the mononuclear phagocyte system (MPS) …

The lack of consensus on bone marrow (BM) and splenic immune cell profiles in preclinical
mouse strains complicates comparative analysis across different studies. Although studies …

Despite the dramatic increase in human lifespan over the past century, there remains
pronounced variability in “health‐span,” or the period of time in which one is generally …

Monocytes circulate the vasculature at steady state and are recruited to sites of inflammation
where they differentiate into macrophages (MФ) to replenish tissue-resident MФ populations …

BTBR T+ tf/J (BTBR) mice have recently been reported to have behaviors that resemble
those of autistic individuals, in that this strain has impairments in social interactions and a …