Comorbidity between major depressive disorder and physical diseases: a comprehensive review of epidemiology, mechanisms and management

M Berk, O Köhler‐Forsberg, M Turner… - World …, 2023 - Wiley Online Library
Populations with common physical diseases–such as cardiovascular diseases, cancer and
neurodegenerative disorders–experience substantially higher rates of major depressive …

Cardiovascular disease and depression: A narrative review

X Li, J Zhou, M Wang, C Yang, G Sun - Frontiers in Cardiovascular …, 2023 - frontiersin.org
In clinical practice, it is frequently observed that cardiac and psychological disorders
frequently co-occur, leading to the emergence of a field known as cardiovascular disease …

Shared genetic loci between depression and cardiometabolic traits

K Torgersen, Z Rahman, S Bahrami, GFL Hindley… - PLoS …, 2022 - journals.plos.org
Epidemiological and clinical studies have found associations between depression and
cardiovascular disease risk factors, and coronary artery disease patients with depression …

Disease trajectories and mortality among individuals diagnosed with depression: a community-based cohort study in UK Biobank

X Han, C Hou, H Yang, W Chen, Z Ying, Y Hu… - Molecular …, 2021 - nature.com
Patients with depression are at increased risk for a range of comorbid diseases, with,
however, unclear explanations. In this large community-based cohort study of the UK …

[HTML][HTML] Prevalence and factors associated with depression and anxiety among older adults: A large-scale cross-sectional study in China

Z He, W Tan, H Ma, Y Shuai, Z Shan, J Zhai… - Journal of affective …, 2024 - Elsevier
Background To determine the prevalence of depression and anxiety among older adults in
China, and explore the associated factors. Methods This cross-sectional study recruited …

Distinct biological signature and modifiable risk factors underlie the comorbidity between major depressive disorder and cardiovascular disease

J Bergstedt, JA Pasman, Z Ma, A Harder… - Nature Cardiovascular …, 2024 - nature.com
Major depressive disorder (MDD) and cardiovascular disease (CVD) are often comorbid,
resulting in excess morbidity and mortality. Here we show that CVDs share most of their …

Effect of modernized collaborative care for depression on depressive symptoms and cardiovascular disease risk biomarkers: eIMPACT randomized controlled trial

JC Stewart, JS Patel, BM Polanka, S Gao… - Brain, Behavior, and …, 2023 - Elsevier
Although depression is a risk and prognostic factor for cardiovascular disease (CVD),
clinical trials treating depression in patients with CVD have not demonstrated cardiovascular …

Melatonin alleviates LPS-induced depression-like behavior in mice by inhibiting ferroptosis by regulating RNA methylation-mediated SIRT6/Nrf2/HO-1 pathway

W Su, J Deng, L Yang, Y Wang, X Gong, J Li - European Journal of …, 2024 - Springer
Purpose The objective of this study is to investigate the impact of ferroptosis on depression
and elucidate the molecular mechanism underlying melatonin's inhibitory effect on …

Observational and genetic analyses of the bidirectional relationship between depression and hypertension

Z Xu, X Wu, C Xiao, W Zhang, P Yan, C Yang… - Journal of Affective …, 2024 - Elsevier
Background While the association between depression and hypertension has been
extensively investigated, the pattern and nature of such association remain inconclusive. We …

Association of educational attainment with esophageal cancer, Barrett's esophagus, and gastroesophageal reflux disease, and the mediating role of modifiable risk …

X Zhang, X Yang, T Zhang, X Yin, J Man… - Frontiers in Public …, 2023 - frontiersin.org
Background Observational studies have reported that educational attainment has been
related to the risk of esophageal cancer (EC) and its precancerous lesions. However, the …