This review is aimed to provide a concise yet extensive survey of key short bioactive peptide
sequences for a range of applications ranging from biomaterials development to peptides …

Abstract Carnosine (β-alanyl-l-histidine) was discovered in 1900 as an abundant non-
protein nitrogen-containing compound of meat. The dipeptide is not only found in skeletal …

Free radicals and other so-called 'reactive species' are constantly produced in the brain in
vivo. Some arise by 'accidents of chemistry', an example of which may be the leakage of …

Modulation of endogenous cellular defense mechanisms represents an innovative approach
to therapeutic intervention in diseases causing chronic tissue damage, such as in …

High-intensity exercise results in reduced substrate levels and accumulation of metabolites
in the skeletal muscle. The accumulation of these metabolites (eg ADP, Pi and H+) can have …

Our aim was to determine changes in free amino acid (FAA) and dipeptide (DP)
concentrations in probable Alzheimer's disease (pAD) subjects compared with control (CT) …

This review focuses on the nature and functional properties of stem cells of the adult
mammalian central nervous system (CNS). It has recently been shown that cell turnover …

The dipeptide carnosine has been observed to exert antiaging activity at cellular and whole
animal levels. This review discusses the possible mechanisms by which carnosine may …

Protein carbonylation induced by reactive carbonyl species (RCS) generated by
peroxidation of polyunsaturated fatty acids plays a significant role in the etiology and/or …

Carnosine (β-alanyl-l-histidine) and homocarnosine (γ-aminobutyryl-l-histidine) are
abundant dipeptides in skeletal muscle and brain of most vertebrates and some …