The subject of crystal engineering started in the 1970s with the study of topochemical
reactions in the solid state. A broad chemical definition of crystal engineering was published …

Infectious diseases, along with cancers, are among the main causes of death among
humans worldwide. The production of therapeutic proteins for treating diseases at large …

Crystallization is an effective, low-cost purification & formulation process widely applied to
pharmaceuticals and fine chemicals. This review describes recent advances in research on …

Crystallization, as a solid–liquid separation process, is employed to purify and isolate a
great diversity of crystalline pharmaceutical products. In recent years, continuous …

With an increasing interest in cocrystals due to various advantages, demand for large-scale
cocrystallization techniques is rising. Solution cocrystallization is a solvent-based approach …

The rejection of process impurities from crystallizing products is an essential step for the
purification of pharmaceutical drugs and for the isolation of active pharmaceutical …

The perfect separation with optimal productivity, yield, and purity is very difficult to achieve.
Despite its high selectivity, in crystallization unwanted impurities routinely contaminate a …

Despite their widespread use for purification, our current methods for the development of
solution crystallization processes lack a sufficient understanding on how impurities …

Interest in the continuous manufacturing in the pharmaceutical industry for the production of
Active Pharmaceutical Ingredients (API's) has greatly increased in recent years. This has led …

Crystallization is one of the important unit operations for the separation and purification of
solid products in the chemical, pharmaceutical, and pesticide industries, especially for …