Circulating tumor cells (CTCs) are tumor cells that have sloughed off the primary tumor and
extravasate into and circulate in the blood. Understanding of the metastatic cascade of CTCs …

Over the past 2 decades, there has been an extraordinary progress in the regimens
developed for the treatment of human epidermal growth factor receptor 2 (HER2)-positive …

Metastasis, the dissemination of cancer cells from primary tumors, represents a major hurdle
in the treatment of cancer. The epithelial-mesenchymal transition (EMT) has been studied in …

BACKGROUND The detection and molecular characterization of circulating tumor cells
(CTCs) are one of the most active areas of translational cancer research, with> 400 clinical …

Circulating tumor cells (CTCs) shed from primary and metastatic cancers are admixed with
blood components and are thus rare, making their isolation and characterization a major …

The primary reason for high mortality rates among cancer patients is metastasis, where
tumor cells migrate through the bloodstream from the original site to other parts of the body …

Ultrasensitive methods have been recently developed to detect circulating tumour cells
(CTCs) in the peripheral blood and disseminated tumour cells (DTCs) in the bone marrow …

During cancer progression, malignant cells undergo epithelial-mesenchymal transitions
(EMT) and mesenchymal-epithelial transitions (MET) as part of a broad invasion and …

Learning Objectives Contrast the current strengths and limitations of the three main slide-
based techniques (IHC, FISH, and CISH) currently in clinical use for testing breast cancer …

We performed a feasibility study to determine the optimal dosage and time of administration
of the monoclonal antibody zirconium‐89 (89Zr)‐trastuzumab to enable positron emission …