Dengue virus infection: a tale of viral exploitations and host responses

N Nanaware, A Banerjee, S Mullick Bagchi, P Bagchi… - Viruses, 2021 - mdpi.com
Dengue is a mosquito-borne viral disease (arboviral) caused by the Dengue virus. It is one
of the prominent public health problems in tropical and subtropical regions with no effective …

Epidemiology, biology, pathogenesis, clinical manifestations, and diagnosis of dengue virus infection, and its trend in Ethiopia: a comprehensive literature review

B Zerfu, T Kassa, M Legesse - Tropical Medicine and Health, 2023 - Springer
Dengue fever is a dengue virus infection, emerging rapidly and posing public health threat
worldwide, primarily in tropical and subtropical countries. Nearly half of the world's …

Evolution and activation mechanism of the flavivirus class II membrane-fusion machinery

MC Vaney, M Dellarole, S Duquerroy, I Medits… - Nature …, 2022 - nature.com
The flavivirus envelope glycoproteins prM and E drive the assembly of icosahedral, spiky
immature particles that bud across the membrane of the endoplasmic reticulum. Maturation …

The Small GTPase Rab14 Regulates the Trafficking of Ceramide from Endoplasmic Reticulum to Golgi Apparatus and Facilitates Classical Swine Fever Virus …

YY Liu, JS Bai, CC Liu, JF Zhou, J Chen… - Journal of …, 2023 - Am Soc Microbiol
Classical swine fever virus (CSFV) is a highly pathogenic RNA virus belonging to the
Flaviviridae family that can cause deadly classical swine fever (CSF) in pigs. However, the …

A prototype-pathogen approach for the development of flavivirus countermeasures

RJ Kuhn, ADT Barrett, AM Desilva… - The Journal of …, 2023 - academic.oup.com
Flaviviruses are a genus within the Flaviviridae family of positive-strand RNA viruses and
are transmitted principally through mosquito and tick vectors. These viruses are responsible …

Flavivirus prM interacts with MDA5 and MAVS to inhibit RLR antiviral signaling

L Sui, Y Zhao, W Wang, H Chi, T Tian, P Wu, J Zhang… - Cell & Bioscience, 2023 - Springer
Background Vector-borne flaviviruses, including tick-borne encephalitis virus (TBEV), Zika
virus (ZIKV), West Nile virus (WNV), yellow fever virus (YFV), dengue virus (DENV), and …

Viral Prototypes for Pandemic Preparedness: The Road Ahead

KM Morabito, MC Cassetti, AJ DeRocco… - The Journal of …, 2023 - academic.oup.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic demonstrated how rapidly
vaccines and monoclonal antibodies (mAbs) could be deployed when the field is prepared …

Flavivirus persistence in wildlife populations

MR Blahove, JR Carter - Viruses, 2021 - mdpi.com
A substantial number of humans are at risk for infection by vector-borne flaviviruses,
resulting in considerable morbidity and mortality worldwide. These viruses also infect wildlife …

The Dynamic Landscape of Capsid Proteins and Viral RNA Interactions in Flavivirus Genome Packaging and Virus Assembly

A Jablunovsky, J Jose - Pathogens, 2024 - mdpi.com
The Flavivirus genus of the Flaviviridae family of enveloped single-stranded RNA viruses
encompasses more than 70 members, many of which cause significant disease in humans …

Cs-GRP78 Recognition Site on Dengue Virus Envelope Protein: in silico perspective

AA Elfiky, A Amr, A Mosaad, AK Mubarak… - Future …, 2023 - Taylor & Francis
Aim: To understand the binding of the dengue virus (DENV) envelope and the host cell
factor, GRP78. Materials & methods: In this study, we simulate the binding of the DENV …