Current understanding of West Nile virus clinical manifestations, immune responses, neuroinvasion, and immunotherapeutic implications
F Bai, EA Thompson, PJS Vig, AA Leis - Pathogens, 2019 - mdpi.com
West Nile virus (WNV) is the most common mosquito-borne virus in North America. WNV-
associated neuroinvasive disease affects all ages, although elderly and …
associated neuroinvasive disease affects all ages, although elderly and …
Cross-Presenting XCR1+ Dendritic Cells as Targets for Cancer Immunotherapy
KM Audsley, AM McDonnell, J Waithman - Cells, 2020 - mdpi.com
The use of dendritic cells (DCs) to generate effective anti-tumor T cell immunity has
garnered much attention over the last thirty-plus years. Despite this, limited clinical benefit …
garnered much attention over the last thirty-plus years. Despite this, limited clinical benefit …
Specific enhancer selection by IRF3, IRF5 and IRF9 is determined by ISRE half-sites, 5′ and 3′ flanking bases, collaborating transcription factors and the chromatin …
Abstract IRF3, IRF5 and IRF9 are transcription factors, which play distinct roles in the
regulation of antiviral and inflammatory responses. The determinants that mediate IRF …
regulation of antiviral and inflammatory responses. The determinants that mediate IRF …
[HTML][HTML] Promoter binding and nuclear retention features of zebrafish IRF family members in IFN response
LL An, X Zhao, XY Gong, YL Li, ZL Qu, HY Sun… - Frontiers in …, 2022 - frontiersin.org
Interferon regulatory factors (IRFs) constitute a family of transcription factors that synchronize
interferon (IFN) antiviral response through translocating to nucleus and binding to the …
interferon (IFN) antiviral response through translocating to nucleus and binding to the …
Two Interferon-Stimulated Response Elements Cooperatively Regulate Interferon-Stimulated Gene Expression in West Nile Virus-Infected IFNAR−/− Mouse Embryo …
D Cui, EE Espínola, K Arora, MA Brinton - Journal of Virology, 2021 - Am Soc Microbiol
We previously identified a subset of interferon-stimulated genes (ISGs) upregulated by West
Nile virus (WNV) infection in wild-type mouse embryo fibroblasts (MEFs) after viral proteins …
Nile virus (WNV) infection in wild-type mouse embryo fibroblasts (MEFs) after viral proteins …
[PDF][PDF] O papel de IRF-5 em células endoteliais e da infecção do sistema nervoso central na patogênese e neurovirulência do vírus Oropouche.
PL Parise - 2024 - repositorio.unicamp.br
RESUMO O vírus Oropouche (OROV) é um arbovírus emergente responsável por milhares
de casos de doença febril exantemática na região Amazônica. Como outros arbovírus …
de casos de doença febril exantemática na região Amazônica. Como outros arbovírus …
In BRCA1 and BRCA2 breast cancers, chromosome breaks occur near herpes tumor virus sequences
B Friedenson - bioRxiv, 2021 - biorxiv.org
Inherited mutations in BRCA1 and BRCA2 genes increase risks for breast, ovarian, and
other cancers. Both genes encode proteins for accurately repairing chromosome breaks. If …
other cancers. Both genes encode proteins for accurately repairing chromosome breaks. If …
Interferon reguláló faktorok DNS kötőhelyeinek genomszintű vizsgálata dendritikus sejtekben
CM Nagyné - 2022 - search.proquest.com
Első tanulmányunkban azokat a jellemzőket határoztuk meg, amelyek lehetővé teszik, hogy
az IRF-ek specifikus genomi helyeken kötődjenek. Az IRF3, IRF5 vagy IRF9 által kötött …
az IRF-ek specifikus genomi helyeken kötődjenek. Az IRF3, IRF5 vagy IRF9 által kötött …