Recent advances in influenza, HIV and SARS-CoV-2 infection prevention and drug treatment—the need for precision medicine

T Kálai, JE Pongrácz, P Mátyus - Chemistry, 2022 - mdpi.com
Viruses, and in particular, RNA viruses, dominate the WHO's current list of ten global health
threats. Of these, we review the widespread and most common HIV, influenza virus, and …

Most monogenic disorders are caused by mutations altering protein folding free energy

P Pandey, E Alexov - International Journal of Molecular Sciences, 2024 - mdpi.com
Revealing the molecular effect that pathogenic missense mutations have on the
corresponding protein is crucial for developing therapeutic solutions. This is especially …

Anti-quorum sensing effects of SidA protein on Escherichia coli receptors: in silico analysis

M Yazdani, M Beihaghi, N Ataee… - Journal of …, 2024 - Taylor & Francis
Quorum sensing enables cell-cell communication in bacteria and regulates biofilm
formation. Biofilm production promotes pathogenicity of Escherichia coli and causes …

Rational approaches to discover SARS-CoV-2/ACE2 interaction inhibitors: Pharmacophore-based virtual screening, molecular docking, molecular dynamics and …

M Yazdani, A Jafari, S Mahdian, M Namazi… - Journal of Molecular …, 2023 - Elsevier
The lack of effective treatment remains a bottleneck in combating the current coronavirus
family pandemic, particularly coronavirus 2019 (COVID-19), which is caused by severe …