The intercalated disc (ID) is a highly specialized structure that connects cardiomyocytes via
mechanical and electrical junctions. Although described in some detail by light microscopy …

Intercalated discs (ICDs) are highly orchestrated structures that connect neighboring
cardiomyocytes in the heart. Three major complexes are distinguished in ICD: desmosome …

Transposable elements (TEs) comprise nearly half of the human genome and are often
transcribed or exhibit cis-regulatory properties with unknown function in specific processes …

Rationale: Loss-of-function of the cardiac sodium channel NaV1. 5 causes conduction
slowing and arrhythmias. NaV1. 5 is differentially distributed within subcellular domains of …

Abstract The cyclic 3′, 5′-adenosine monophosphate (cAMP) signalling pathway
constitutes an ancient signal transduction pathway present in prokaryotes and eukaryotes …

Background Variants of the desmosomal protein desmoplakin are associated with
arrhythmogenic cardiomyopathy, an important cause of ventricular arrhythmias in children …

Aging is the main risk factor for cardiovascular diseases. In humans, cardiac aging remains
poorly characterized. Most studies are based on chronological age (CA) and disregard …

The Popeye domain containing (POPDC) gene family consists of POPDC1 (also known as
BVES), POPDC2 and POPDC3 and encodes a novel class of cyclic adenosine …

Background Limb‐girdle muscular dystrophy (LGMD) comprises a heterogeneous group of
diseases, affecting different muscles, predominantly skeletal muscles and cardiac muscles …

Objective The Popeye domain containing 3 (POPDC3) gene encodes a membrane protein
involved in cyclic adenosine monophosphate (cAMP) signaling. Besides gastric cancer, no …