Remodeling of large and small arteries contributes to the development and complications of
hypertension. The focus of this review is some of the mechanisms involved in the …

Background—The high incidence of aortic disease in subjects with congenital aortic valve
malformations suggests a causative relationship between these 2 conditions. The …

Apoptosis (programmed cell death) of vascular smooth muscle cells (VSMCs) has recently
been identified as an important process in a variety of human vascular diseases, including …

Vascular changes in gliomas were analyzed by implanting fluorescent-labeled glioma 261
cells in the brains of 28 mice. Seven animals were killed each week for 4 weeks. We …

Regulation of vascular smooth muscle cell growth is critical to the maintenance of normal
blood flow and vessel patency. Angiotensin-(1–7)[Ang-(1–7)] inhibits proliferation of …

In the last decade, apoptosis (or programmed cell death) has become appreciated as an
important process in the development of the cardiovascular system. Moreover, apoptosis …

Morphogenesis and developmental remodeling of cardiovascular tissues involve
coordinated regulation of cell proliferation and apoptosis. In the heart, clear evidence points …

Amino acids modulate the secretion of both insulin and glucagon; the composition of dietary
protein therefore has the potential to influence the balance of glucagon and insulin activity …

Evidence is increasing in hypertensive models for an inflammatory reaction in the
microcirculation with abnormal leukocyte counts and adhesion to the endothelium …

The angiotensin AT2 receptor subtype was recently cloned and pharmacologically
characterized but its function still remains elusive and controversial. It is a member of the G …