Silk fibroin has become a prominent material in tissue engineering (TE) over the last 20
years with almost 10,000 published works spanning in all the TE applications, from skeleton …

Silk refers to a family of natural fibers spun by several species of invertebrates such as
spiders and silkworms. In particular, silkworm silk, the silk spun by Bombyx mori larvae, has …

The repair of the central nervous system (CNS) is a major challenge because of the difficulty
for neurons or axons to regenerate after damages. Injectable hydrogels have been …

Encapsulated stem cells in various biomaterials have become a potentially promising cell
transplantation strategy in the treatment of various neurologic disorders. However, there is …

Silk fibroin, a natural macromolecular protein without physiological activity, has been widely
used in different fields, such as the regeneration of bones, cartilage, nerves, and other …

Ischemic stroke represents one of the most prevalent pathologies in humans and is a
leading cause of death and disability. Anti-thrombolytic therapy with tissue plasminogen …

Silk can be processed into a broad spectrum of material formats and is explored for a wide
range of medical applications, including hydrogels for wound care. The current paradigm is …

Current pharmacological and surgical therapies for the central nervous system (CNS) show
a limited capacity to reduce the damage progression; that together with the intrinsic limited …

Targeting the brain cavity formed by an ischemic stroke is appealing for many regenerative
treatment strategies but requires a robust delivery technology. We hypothesized that self …

Stem cell transplantation with rehabilitation therapy presents an effective stroke treatment.
Here, we discuss current breakthroughs in stem cell research along with rehabilitation …