In this work, we outlined an experimental workflow enabling the rapid assessment of primary
and secondary nucleation and crystal growth kinetics. We used small-scale experiments in …

The effect of fluid shear on the primary nucleation of paracetamol in water, isopropyl alcohol,
and acetonitrile was investigated. First, experiments were performed with a Taylor–Couette …

Improving the flexibility and capabilities of pharmaceutical technologies and lowering the
process development time while satisfying regulatory constraints translate to highly desired …

Despite the ubiquity of the crystallization of sodium chloride (NaCl) throughout history, few
detailed, well-controlled quantitative studies of the kinetics of NaCl crystallization have been …

Process developers in the pharmaceutical industry lack readily deployable, standardized, off-
the-shelf continuous crystallizers (< 100 mL), abiding the low material requirements of early …

A Couette cell flow device was designed, and an experimental procedure was developed to
enable a quantitative study of the effects of fluid shear on secondary nucleation using a fixed …

Crystal nucleation is crucial in various fields of science and technology, ranging from
materials synthesis to pharmaceutical production. Our research aims to determine the …

Crystal nucleation is a key event in the process of crystallization and is important in a
number of processes in the pharmaceutical industry. Nucleation kinetics impact the crystal …