Ion interference therapy of tumors based on inorganic nanoparticles

Y Chi, P Sun, Y Gao, J Zhang, L Wang - Biosensors, 2022 - mdpi.com
As an essential substance for cell life activities, ions play an important role in controlling cell
osmotic pressure balance, intracellular acid–base balance, signal transmission, biocatalysis …

Strategies of perturbing ion homeostasis for cancer therapy

DY Lee, JH Ha, M Kang, Z Yang, W Jiang… - Advanced …, 2022 - Wiley Online Library
Perturbing ion homeostasis has emerged as a novel therapeutic strategy for enhanced
cancer therapy. Intensive development of ion homeostasis‐disturbing agents has been …

A Pyridyl-Linked Benzimidazolyl Tautomer Facilitates Prodigious H+/Cl Symport through a Cooperative Protonation and Chloride Ion Recognition

A Mondal, JA Malla, H Paithankar, S Sharma… - Organic …, 2021 - ACS Publications
We report two pyridyl-linked benzimidazolyl hydrazones as HCl cotransporters that are 5
and 2 times superior to prodigiosin, a natural product whose transport efficiency has never …

Novel anthraquinone derivatives trigger endoplasmic reticulum stress response and induce apoptosis

H Zhai, C Wang, J Li, D Liang, F Li… - Future Medicinal …, 2023 - Taylor & Francis
Background: Endoplasmic reticulum (ER) stress is a therapeutic target in cancer given its
regulation of bioenergetics and cell death. Methodology & results: We synthesized 14 ER …