Carcinoembryonic antigen (CEA) and hepatic metastasis in colorectal cancer: update on biomarker for clinical and biotechnological approaches

M Campos-da-Paz, JG Dórea… - Recent patents on …, 2018 - ingentaconnect.com
Background: Carcinoembryonic Antigen (CEA) is a recommended prognostic marker in
Colorectal Cancer (CRC) for tumor diagnosis and monitoring response to therapy. High CEA …

Radioimmunotherapy in oncology: overview of the last decade clinical trials

A Rondon, J Rouanet, F Degoul - Cancers, 2021 - mdpi.com
Simple Summary Monoclonal antibody-bearing radionuclides have been under clinical
investigation over the last two decades for their use in theranostic (diagnostic and …

Multivalent ligand: design principle for targeted therapeutic delivery approach

C Chittasupho - Therapeutic delivery, 2012 - Taylor & Francis
Multivalent interactions of biological molecules play an important role in many biochemical
events. A multivalent ligand comprises of multiple copies of ligands conjugated to scaffolds …

Carrier systems of radiopharmaceuticals and the application in cancer therapy

T Zhang, H Lei, X Chen, Z Dou, B Yu, W Su… - Cell Death …, 2024 - nature.com
Radiopharmaceuticals play a vital role in cancer therapy. The carrier of
radiopharmaceuticals can precisely locate and guide radionuclides to the target, where …

General overview of radioimmunotherapy of solid tumors

I Navarro-Teulon, C Lozza, A Pèlegrin, E Vivès… - …, 2013 - Taylor & Francis
Radioimmunotherapy (RIT) represents an attractive tool for the treatment of local and/or
diffuse tumors with radiation. In RIT, cytotoxic radionuclides are delivered by monoclonal …

[HTML][HTML] Radioimmunotheragnosis in Cancer Research

G Garaulet, BB Báez, G Medrano, M Rivas-Sánchez… - …, 2024 - pmc.ncbi.nlm.nih.gov
Simple Summary ImmunoPET involves tagging an antibody (a protein that targets cancer
cells) with a radioactive substance that can be seen by imaging. This could non-invasively …

[PDF][PDF] Immunoscintigraphy and radioimmunotherapy in cuba: experiences with labeled monoclonal antibodies for cancer diagnosis and treatment (1993-2013)

Y Peña, A Perera, JF Batista - MEDICC review, 2014 - SciELO Public Health
ABSTRACT INTRODUCTION: The availability of monoclonal antibodies in Cuba has
facilitated development and application of innovative techniques (immunoscintigraphy and …

Antibody fragment and targeted colorectal cancer therapy: A global systematic review

S Ghani, N Deravi, M Pirzadeh, B Rafiee… - Current …, 2022 - ingentaconnect.com
Background and Aims: Antibody-based therapeutics have been shown to be promising for
the treatment of colorectal cancer patients. However, the size and long-circulating half-lives …

[HTML][HTML] Radiofármacos en inmunocentelleografía y radioinmunoterapia

R Leyva Montaña, A Perera, JA Morín Zorrilla - Nucleus, 2012 - scielo.sld.cu
La alta morbilidad y letalidad del cáncer, hacen que esta enfermedad se considere, tanto en
Cuba como en el mundo, un serio problema de salud. La radioimmunodiagnosis y la …

[PDF][PDF] 含组氨酸标签的小分子抗体临床应用现状

刘晓, 屈琳, 黄昌发, 余馨, 罗勤 - 中国医药生物技术, 2012 - cmbp.net.cn
单链抗体(scFv) 是由免疫球蛋白的重链可变区(VH) 和轻链可变区(VL) 通过一条连接肽,
如(GGGGS) 4 连接而成的小分子抗体(图1). 与全抗相比, 它因分子小, 容易进入实体肿瘤 …