Eye is the unique sense organ with complex and sophisticated anatomy and physiology.
Being most instrumental for vision, it is secured by varied protective barriers; ranging from …

Over the last years, the scientific interest about topical ocular delivery targeting the posterior
segment of the eye has been increasing. This is probably due to the fact that this is a non …

Erythropoietin (EPO) is known for its neuroprotective and neuroregenerative properties. EPO
topical ocular administration has not been tested yet and its bioavailability could be …

Objective The first aim of this study was to develop a nanocarrier that could transport the
peroxisome proliferator-activated receptor agonist, pioglitazone (PGZ) across brain …

Topical instillation of drugs targeting the posterior ocular segment is an expanding area of
research. Chitosan and hyaluronic acid have remarkable mucoadhesive properties and …

Purpose The main goal of this study was to encapsulate Pioglitazone (PGZ), in
biodegradable polymeric nanoparticles as a new strategy for the treatment of ocular …

Aim: Utility of cow ghee (CG) as permeation enhancer in development of topical ocular
microemulsion (ME) for delivery of fluocinolone acetonide (FA) to posterior eye. Methods …

Topical route of administration is very important and the most commonly used method of
drug delivery for treatment of ocular diseases. However, due to unique anatomical and …

Introduction: The sclera is considered the 'static barrier,'a main barrier for transscleral drug
delivery. The characterization of passive and iontophoretic transport across the sclera in …

Neuroprotection in glaucoma using epoetin beta (EPOβ) has yielded promising results. Our
team has developed chitosan-hyaluronic acid nanoparticles (CS/HA) designed to carry …