The neuropathology of traumatic brain injury

AC Mckee, DH Daneshvar - Handbook of clinical neurology, 2015 - Elsevier
Traumatic brain injury, a leading cause of mortality and morbidity, is divided into three
grades of severity: mild, moderate, and severe, based on the Glasgow Coma Scale, the loss …

Alzheimer disease: epidemiology, diagnostic criteria, risk factors and biomarkers

C Reitz, R Mayeux - Biochemical pharmacology, 2014 - Elsevier
The global prevalence of dementia is as high as 24 million, and has been predicted to
quadruple by the year 2050. In the US alone, Alzheimer disease (AD)–the most frequent …

Epidemiology of Alzheimer disease

R Mayeux, Y Stern - Cold Spring Harbor …, 2012 - perspectivesinmedicine.cshlp.org
The global prevalence of dementia has been estimated to be as high as 24 million, and is
predicted to double every 20 years until at least 2040. As the population worldwide …

Epidemiology of Alzheimer disease

C Reitz, C Brayne, R Mayeux - Nature Reviews Neurology, 2011 - nature.com
The global prevalence of dementia is estimated to be as high as 24 million, and is predicted
to double every 20 years through to 2040, leading to a costly burden of disease. Alzheimer …

[HTML][HTML] The neuropathology and neurobiology of traumatic brain injury

K Blennow, J Hardy, H Zetterberg - Neuron, 2012 - cell.com
The acute and long-term consequences of traumatic brain injury (TBI) have received
increased attention in recent years. In this Review, we discuss the neuropathology and …

Chronic traumatic encephalopathy in athletes: progressive tauopathy after repetitive head injury

AC McKee, RC Cantu, CJ Nowinski… - … of Neuropathology & …, 2009 - academic.oup.com
Since the 1920s, it has been known that the repetitive brain trauma associated with boxing
may produce a progressive neurological deterioration, originally termed dementia …

The molecular pathophysiology of concussive brain injury

G Barkhoudarian, DA Hovda… - Clinics in sports …, 2011 - sportsmed.theclinics.com
Concussion (or mild traumatic brain injury, mTBI) is a biomechanically induced neurological
injury, resulting in an alteration of mental status, such as confusion or amnesia, which may …

Candidate mechanisms for chemotherapy-induced cognitive changes

TA Ahles, AJ Saykin - Nature Reviews Cancer, 2007 - nature.com
The mechanism (s) for chemotherapy-induced cognitive changes are largely unknown;
however, several candidate mechanisms have been identified. We suggest that shared …

Traumatic brain injury and amyloid-β pathology: a link to Alzheimer's disease?

VE Johnson, W Stewart, DH Smith - Nature Reviews Neuroscience, 2010 - nature.com
Traumatic brain injury (TBI) has devastating acute effects and in many cases seems to
initiate long-term neurodegeneration. Indeed, an epidemiological association between TBI …

The molecular pathophysiology of concussive brain injury–an update

G Barkhoudarian, DA Hovda… - Physical Medicine and …, 2016 - pmr.theclinics.com
Concussion (mild traumatic brain injury [TBI]), particularly with organized sports, has come to
the forefront of popular culture. Affecting about 1.6 million to 3.8 million athletes a year, its …