Great progress has been made in recent years to reduce the high level of suffering caused
by malaria worldwide. Notably, the use of insecticide-treated mosquito nets for malaria …

Antimalarial drugs (eg chloroquine and its close structural analogues) were developed
primarily to treat malaria; however, they are beneficial for many dermatological …

Microglia are important immune cells in the central nervous system (CNS) that undergo
turnover throughout the lifespan. If microglial debris is not removed in a timely manner …

Highlights•Chloroquine is used for anti-malaria, anti-cancer and anti-virus treatment.•The
efficacy of hydroxychloroquine against COVID-19 is controversial.•Several quinoline …

In December 2019, the novel coronavirus disease pandemic (COVID-19) that began in
China had infected so far more than 109,217,366 million individuals worldwide and …

The 5‐(4‐aryl azo)‐8‐hydroxyquinolines (L1–L3) and their metal complexes with Ni2+ and
Zn2+ have been produced. Various spectroscopic techniques have been employed to …

Spinal cord injury (SCI) is catastrophic to humans and society. However, there is currently no
effective treatment for SCI. Autophagy is known to serve critical roles in both the …

Based on medicinal chemistry tools, new compounds for malaria treatment were designed.
The scaffolds of the drugs used to treat malaria, such as chloroquine, primaquine …

Abstract This combined Al12 E 12 (E= N, P) surface adsorption and docking study describes
the new possibility of prospective potential probing (photophysical/optical) and therapy …

Malaria has been a major parasitic disease in tropical and subtropical regions and is
estimated to kill between one and two million people (mainly children) every year. Novel anti …