B vitamins and their role in immune regulation and cancer

CT Peterson, DA Rodionov, AL Osterman, SN Peterson - Nutrients, 2020 - mdpi.com
B group vitamins represent essential micronutrients for myriad metabolic and regulatory
processes required for human health, serving as cofactors used by hundreds of enzymes …

Biological Properties of Vitamins of the B-Complex, Part 1: Vitamins B1, B2, B3, and B5

M Hrubša, T Siatka, I Nejmanová, M Vopršalová… - Nutrients, 2022 - mdpi.com
This review summarizes the current knowledge on essential vitamins B1, B2, B3, and B5.
These B-complex vitamins must be taken from diet, with the exception of vitamin B3, that can …

[HTML][HTML] Intermediate role of gut microbiota in vitamin B nutrition and its influences on human health

Z Wan, J Zheng, Z Zhu, L Sang, J Zhu, S Luo… - Frontiers in …, 2022 - frontiersin.org
Vitamin B consists of a group of water-soluble micronutrients that are mainly derived from
the daily diet. They serve as cofactors, mediating multiple metabolic pathways in humans. As …

Functional roles of B‐vitamins in the gut and gut microbiome

T Uebanso, T Shimohata, K Mawatari… - Molecular nutrition & …, 2020 - Wiley Online Library
The gut microbiota produce hundreds of bioactive compounds, including B‐vitamins, which
play significant physiological roles in hosts by supporting the fitness of symbiotic species …

The influence of alcohol consumption on intestinal nutrient absorption: a comprehensive review

M Butts, VL Sundaram, U Murughiyan, A Borthakur… - Nutrients, 2023 - mdpi.com
Chronic alcohol use has been attributed to the development of malnutrition. This is in part
due to the inhibitory effect of ethanol on the absorption of vital nutrients, including glucose …

Sodium-coupled glucose transport, the SLC5 family, and therapeutically relevant inhibitors: from molecular discovery to clinical application

G Gyimesi, J Pujol-Giménez, Y Kanai… - Pflügers Archiv-European …, 2020 - Springer
Sodium glucose transporters (SGLTs) belong to the mammalian solute carrier family SLC5.
This family includes 12 different members in human that mediate the transport of sugars …

Regulation of coenzyme A levels by degradation: the 'Ins and Outs'

P Naquet, EW Kerr, SD Vickers, R Leonardi - Progress in lipid research, 2020 - Elsevier
Coenzyme A (CoA) is the predominant acyl carrier in mammalian cells and a cofactor that
plays a key role in energy and lipid metabolism. CoA and its thioesters (acyl-CoAs) regulate …

Gut microbial metabolite-mediated regulation of the intestinal barrier in the pathogenesis of inflammatory bowel disease

N Iyer, SC Corr - Nutrients, 2021 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic inflammatory disease. The disease has a
multifactorial aetiology, involving genetic, microbial as well as environmental factors. The …

Biotin deficiency enhances the inflammatory response of human dendritic cells

S Agrawal, A Agrawal, HM Said - American Journal of …, 2016 - journals.physiology.org
The water-soluble biotin (vitamin B7) is indispensable for normal human health. The vitamin
acts as a cofactor for five carboxylases that are critical for fatty acid, glucose, and amino acid …

Cerebral vitamin B5 (D-pantothenic acid) deficiency as a potential cause of metabolic perturbation and neurodegeneration in Huntington's disease

S Patassini, P Begley, J Xu, SJ Church, N Kureishy… - Metabolites, 2019 - mdpi.com
Huntington's disease (HD) is a neurodegenerative disorder caused by an expanded CAG
repeat in exon 1 of the HTT gene. HD usually manifests in mid-life with loss of GABAergic …