Residual dipolar couplings in structure determination of natural products

GW Li, H Liu, F Qiu, XJ Wang, XX Lei - Natural products and …, 2018 - Springer
The determination of natural products stereochemistry remains a formidable task. Residual
dipolar couplings (RDCs) induced by anisotropic media are a powerful tool for determination …

Computer‐assisted 3D structure elucidation of natural products using residual dipolar couplings

E Troche‐Pesqueira, C Anklin, RR Gil… - Angewandte Chemie …, 2017 - Wiley Online Library
An enhanced computer‐assisted procedure for the determination of the relative
configuration of natural products, which starts from the molecular formula and uses a …

Measurement of Residual Dipolar Couplings of Organic Molecules in Multiple Solvent Systems Using a Liquid‐Crystalline‐Based Medium

SY Qin, Y Jiang, H Sun, H Liu, AQ Zhang… - Angewandte …, 2020 - Wiley Online Library
Residual dipolar coupling (RDC), a robust anisotropic NMR parameter for structural
elucidation of organic molecules, is only accessible in an anisotropic environment. Herein …

Light-controlled lyotropic liquid crystallinity of polyaspartates exploited as photo-switchable alignment medium

M Hirschmann, O Soltwedel, P Ritzert… - Journal of the …, 2023 - ACS Publications
Two polyaspartates bearing ortho-fluorinated azobenzenes (p FAB) as photo-responsive
groups in the side chain were synthesized: P p FABLA (1) and co-polyaspartate PpFABLA …

Perspectives in the application of residual dipolar couplings in the structure elucidation of weakly aligned small molecules

V Schmidts - Magnetic Resonance in Chemistry, 2017 - Wiley Online Library
This perspective article aims to review the general methodology in the application of
residual dipolar couplings (RDCs) in the structure elucidation of small molecules and give …

A self‐assembled oligopeptide as a versatile NMR alignment medium for the measurement of residual dipolar couplings in methanol

X Lei, F Qiu, H Sun, L Bai, WX Wang… - Angewandte Chemie …, 2017 - Wiley Online Library
Residual dipolar coupling (RDC) is a powerful structural parameter for the determination of
the constitution, conformation, and configuration of organic molecules. Herein, we report the …

Development of new supramolecular lyotropic liquid crystals and their application as alignment media for organic compounds

M Leyendecker, NC Meyer, CM Thiele - Angewandte Chemie, 2017 - Wiley Online Library
Most alignment media for the residual dipolar coupling (RDC) based molecular structure
determination of small organic compounds consist of rod‐like polymers dissolved in organic …

An alignment medium for measuring residual dipolar couplings in pure DMSO: Liquid crystals from graphene oxide grafted with polymer brushes

W Zong, GW Li, JM Cao, X Lei, ML Hu… - Angewandte Chemie …, 2016 - Wiley Online Library
Residual dipolar couplings (RDCs) have attracted attention in light of their great impact on
the structural elucidation of organic molecules. However, the effectiveness of RDC …

Programmable alignment media from self-assembled oligopeptide amphiphiles for the measurement of independent sets of residual dipolar couplings in organic …

Y Lin, J Li, SY Qin, H Sun, YL Yang… - Chemical …, 2022 - pubs.rsc.org
NMR spectroscopy in anisotropic media has emerged as a powerful technique for the
structural elucidation of organic molecules. Its application requires weak alignment of …

An Acrylonitrile‐Based Copolymer Gel as an NMR Alignment Medium for Extraction of Residual Dipolar Couplings of Small Molecules in Aqueous Solution

DS Carvalho, DGB da Silva, F Hallwass… - …, 2023 - Wiley Online Library
An NMR weakly‐aligning polymer gel has been prepared by copolymerization of
acrylonitrile and 2‐acrylamide‐2‐methyl‐1‐propanesulfonic acid in the presence of 1, 4 …