The sheep as a large animal model for the investigation and treatment of human disorders

A Banstola, JNJ Reynolds - Biology, 2022 - mdpi.com
Simple Summary We review the value of large animal models for improving the translation of
biomedical research for human application, focusing primarily on sheep. Abstract An …

Biomechanical and clinical studies on lumbar spine fusion surgery: a review

K Pradeep, B Pal - Medical & Biological Engineering & Computing, 2023 - Springer
Low back pain is associated with degenerative disc diseases of the spine. Surgical
treatment includes fusion and non-fusion types. The gold standard is fusion surgery, wherein …

Relationship between intervertebral disc and facet joint degeneration: a probabilistic finite element model study

M Bashkuev, S Reitmaier, H Schmidt - Journal of biomechanics, 2020 - Elsevier
Both intervertebral disc (IVD) and facet joint (FJ) degeneration are frequently associated with
chronic low back pain. While genetic factors are considered the most relevant in the onset of …

Thermodynamics-based stability criteria for constitutive equations of isotropic hyperelastic solids

K Upadhyay, G Subhash, D Spearot - Journal of the Mechanics and Physics …, 2019 - Elsevier
A generalized thermodynamic stability criterion for isotropic finite elastic solids is derived
using the fundamental balance laws and field equations of continuum mechanics, which is …

Numerical prediction of the mechanical failure of the intervertebral disc under complex loading conditions

G Casaroli, T Villa, T Bassani, N Berger-Roscher… - Materials, 2017 - mdpi.com
Finite element modeling has been widely used to simulate the mechanical behavior of the
intervertebral disc. Previous models have been generally limited to the prediction of the disc …

Annulus fibrosus functional extrafibrillar and fibrous mechanical behaviour: experimental and computational characterisation

M Mengoni, O Kayode, SNF Sikora… - Royal Society …, 2017 - royalsocietypublishing.org
The development of current surgical treatments for intervertebral disc damage could benefit
from virtual environment accounting for population variations. For such models to be …

Three-dimensional microstructural reconstruction of the ovine intervertebral disc using ultrahigh field MRI

M Sharabi, KR Wade, F Galbusera, V Rasche… - The Spine Journal, 2018 - Elsevier
BACKGROUND The intervertebral disc (IVD) is a complex organ that acts as a flexible
coupling between two adjacent vertebral bodies and must therefore accommodate …

An ex-vivo model for the biomechanical assessment of cement discoplasty

S Ghandour, K Pazarlis, S Lewin, P Isaksson… - … in Bioengineering and …, 2022 - frontiersin.org
Percutaneous Cement Discoplasty (PCD) is a surgical technique developed to relieve pain
in patients with advanced degenerative disc disease characterized by a vacuum …

Mechanical and biological characterization of a composite annulus fibrosus repair strategy in an endplate delamination model

D Alexeev, S Cui, S Grad, Z Li, SJ Ferguson - Jor Spine, 2020 - Wiley Online Library
This study compares the mechanical response of the commonly used annulus fibrosus (AF)
puncture injury model of the intervertebral disc (IVD) and a newly proposed AF failure at the …

Spinal stability analysis of lumbar interbody fusion according to pelvic type and cage angle based on simplified spinal model with various pelvic indices

CJ Kim, SM Son, SH Choi, D Ryu… - Frontiers in Bioengineering …, 2022 - frontiersin.org
Recently, the objectives of lumbar interbody fusion (LIF) have been extended to include the
correction of broader/relative indications in addition to spinal fixation. Accordingly, LIF must …