Making a new limb out of old cells: exploring endogenous cell reprogramming and its role during limb regeneration
MJ Raymond Jr, CD McCusker - American Journal of …, 2024 - journals.physiology.org
Cellular reprogramming is characterized by the induced dedifferentiation of mature cells into
a more plastic and potent state. This process can occur through artificial reprogramming …
a more plastic and potent state. This process can occur through artificial reprogramming …
Loss of the ability to regenerate body appendages in vertebrates: from side effects of evolutionary innovations to gene loss
AG Zaraisky, KR Araslanova, AD Shitikov… - Biological …, 2024 - Wiley Online Library
The ability to regenerate large body appendages is an ancestral trait of vertebrates, which
varies across different animal groups. While anamniotes (fish and amphibians) commonly …
varies across different animal groups. While anamniotes (fish and amphibians) commonly …
Molecular basis for positional memory and its reprogrammability in limb regeneration
L Otsuki, SA Plattner, Y Taniguchi-Sugiura, EM Tanaka - bioRxiv, 2023 - biorxiv.org
Upon limb amputation in salamanders, anterior and posterior connective tissue cells form
distinct signalling centres that together fuel successful regeneration. The molecular …
distinct signalling centres that together fuel successful regeneration. The molecular …
Development of a model system to study the regulation of patterning competency in regenerating axolotl limbs
M Raymond, W Vieira, S Manon, M Cherubino… - 2023 - researchsquare.com
Limb regeneration in the Mexican axolotl requires the dedifferentiation of mature limb cells
into progenitor cells known as blastema cells. The blastema cells become competent to the …
into progenitor cells known as blastema cells. The blastema cells become competent to the …