Regional diversity of the gastrointestinal microbiome

K Martinez-Guryn, V Leone, EB Chang - Cell host & microbe, 2019 - cell.com
The role of gut microbes in health and disease has often been surmised from stool, which is
easily sampled and rich in microbial diversity, density, and abundance. Microbial analyses …

Visualization of metabolites and microbes at high spatial resolution using MALDI mass spectrometry imaging and in situ fluorescence labeling

P Bourceau, B Geier, V Suerdieck, T Bien… - Nature …, 2023 - nature.com
Label-free molecular imaging techniques such as matrix-assisted laser desorption ionization
mass spectrometry imaging (MALDI-MSI) enable the direct and simultaneous mapping of …

A microbial transporter of the dietary antioxidant ergothioneine

DG Dumitrescu, EM Gordon, Y Kovalyova… - Cell, 2022 - cell.com
Summary Low-molecular-weight (LMW) thiols are small-molecule antioxidants required for
the maintenance of intracellular redox homeostasis. However, many host-associated …

A symbiotic physical niche in Drosophila melanogaster regulates stable association of a multi-species gut microbiota

R Dodge, EW Jones, H Zhu, B Obadia… - Nature …, 2023 - nature.com
The gut is continuously invaded by diverse bacteria from the diet and the environment, yet
microbiome composition is relatively stable over time for host species ranging from …

Pseudomonas aeruginosa breaches respiratory epithelia through goblet cell invasion in a microtissue model

AL Swart, BJ Laventie, R Sütterlin, T Junne… - Nature …, 2024 - nature.com
Pseudomonas aeruginosa, a leading cause of severe hospital-acquired pneumonia, causes
infections with up to 50% mortality rates in mechanically ventilated patients. Despite some …

Bacterial chemotaxis in human diseases

B Zhou, CM Szymanski, A Baylink - Trends in Microbiology, 2023 - cell.com
To infect and cause disease, bacterial pathogens must localize to specific regions of the host
where they possess the metabolic and defensive acumen for survival. Motile flagellated …

Highly oxidized oxide surface toward optimum oxygen evolution reaction by termination engineering

X Li, L Ge, Y Du, H Huang, Y Ha, Z Fu, Y Lu, W Yang… - ACS …, 2023 - ACS Publications
The oxygen evolution reaction (OER) is a critical step for sustainable fuel production through
electrochemistry process. Maximizing active sites of nanocatalyst with enhanced intrinsic …

The importance of host physical niches for the stability of gut microbiome composition

WB Ludington - … Transactions of the Royal Society B, 2024 - royalsocietypublishing.org
Gut bacteria are prevalent throughout the Metazoa and form complex microbial communities
associated with food breakdown, nutrient provision and disease prevention. How hosts …

An Overview of Helicobacter pylori Survival Tactics in the Hostile Human Stomach Environment

YY Cheok, CYQ Lee, HC Cheong, J Vadivelu, CY Looi… - Microorganisms, 2021 - mdpi.com
Helicobacter pylori is well established as a causative agent for gastritis, peptic ulcer, and
gastric cancer. Armed with various inimitable virulence factors, this Gram-negative bacterium …

Gastric stem cells promote inflammation and gland remodeling in response to Helicobacter pylori via Rspo3‐Lgr4 axis

J Wizenty, S Müllerke, M Kolesnichenko… - The EMBO …, 2022 - embopress.org
Helicobacter pylori is a pathogen that colonizes the stomach and causes chronic gastritis.
Helicobacter pylori can colonize deep inside gastric glands, triggering increased R‐spondin …