Over the past decade there has been an increasing reliance on strong opioids to treat acute
and chronic pain, which has been associated with a rising epidemic of prescription opioid …

Chronic pain is a condition in which pain progresses from an acute to chronic state and
persists beyond the healing process. Chronic pain impairs function and decreases patients' …

Spinal cord stimulation (SCS) is a minimally invasive therapy used for the treatment of
chronic neuropathic pain. SCS is a safe and effective alternative to medications such as …

The role of peripheral physiology in the experience of emotion has been debated since the
19th century following the seminal proposal by William James that somatic responses to …

Pain is a subjective sensory experience that can, mostly, be reported but cannot be directly
measured or quantified. Nevertheless, a suite of biomarkers related to mechanisms, neural …

Fibromyalgia is characterized by widespread pain, fatigue, sleep disturbances and other
symptoms, and has a substantial socioeconomic impact. Current biomedical and …

The amygdala is a limbic brain region that plays a key role in emotional processing,
neuropsychiatric disorders, and the emotional‐affective dimension of pain. Preclinical and …

Pain has a strong emotional component and is defined by its unpleasantness. Chronic pain
represents a complex disorder with anxio-depressive symptoms and cognitive deficits …

Aim To provide an overview of mechanisms underlying craniofacial pain; to highlight
peripheral and central adaptations that may promote chronification of pain in craniofacial …

Osteopathy is a person-centred healthcare discipline that emphasizes the body's structure-
function interrelationship—and its self-regulatory mechanisms—to inform a whole-person …