An overview of global GBS epidemiology

K Le Doare, PT Heath - Vaccine, 2013 - Elsevier
Streptococcus agalactiae (group B streptococcus (GBS)), remains the leading cause of
neonatal sepsis and meningitis in many countries and an important cause of disease in …

Epidemiology of group B streptococcal disease in the United States: shifting paradigms

A Schuchat - Clinical microbiology reviews, 1998 - Am Soc Microbiol
Since its emergence 25 years ago, group B streptococcus has become recognized as a
cause of serious illness in newborns, pregnant women, and adults with chronic medical …

Stratification of risk of early-onset sepsis in newborns≥ 34 weeks' gestation

GJ Escobar, KM Puopolo, S Wi, BJ Turk… - …, 2014 - publications.aap.org
OBJECTIVE: To define a quantitative stratification algorithm for the risk of early-onset sepsis
(EOS) in newborns≥ 34 weeks' gestation. METHODS: We conducted a retrospective nested …

Antibiotic therapy for reduction of infant morbidity after preterm premature rupture of the membranes: a randomized controlled trial

BM Mercer, M Miodovnik, GR Thurnau, RL Goldenberg… - Jama, 1997 - jamanetwork.com
Context.—Intrauterine infection is thought to be one cause of preterm premature rupture of
the membranes (PPROM). Antibiotic therapy has been shown to prolong pregnancy, but the …

Impaired neutrophil extracellular trap (NET) formation: a novel innate immune deficiency of human neonates

CC Yost, MJ Cody, ES Harris… - Blood, The Journal …, 2009 - ashpublications.org
Neutrophils are highly specialized innate effector cells that have evolved for killing of
pathogens. Human neonates have a common multifactorial syndrome of neutrophil …

Risk factors and opportunities for prevention of early-onset neonatal sepsis: a multicenter case-control study

A Schuchat, SS Zywicki, MJ Dinsmoor, B Mercer… - …, 2000 - publications.aap.org
Background. Early-onset group B streptococcal (GBS) prevention efforts are based on
targeted use of intrapartum antibiotic prophylaxis (IAP); applicability of these prevention …

The accuracy of late antenatal screening cultures in predicting genital group B streptococcal colonization at delivery

MK Yancey, A Schuchat, LK Brown, VL Ventura… - Obstetrics & …, 1996 - Elsevier
OBJECTIVE: To determine the accuracy of late antenatal anogenital cultures in predicting
group B Streptococcal colonization at delivery. METHODS: Swabs of the vagina and rectum …

Changing epidemiology of group B streptococcal colonization

ME Hickman, MA Rench, P Ferrieri, CJ Baker - Pediatrics, 1999 - publications.aap.org
Objectives. To define factors influencing vertical transmission of and neonatal colonization
with group B streptococci (GBS) in neonates representing ethnically and economically …

Identification of group B streptococcal Sip protein, which elicits cross-protective immunity

BR Brodeur, M Boyer, I Charlebois, J Hamel… - Infection and …, 2000 - Am Soc Microbiol
ABSTRACT A protein of group B streptococci (GBS), named Sip for surface immunogenic
protein, which is distinct from previously described surface proteins, was identified after …

Active bacterial core surveillance of the emerging infections program network.

A Schuchat, T Hilger, E Zell, MM Farley… - Emerging infectious …, 2001 - ncbi.nlm.nih.gov
Abstract Active Bacterial Core surveillance (ABCs) is a collaboration between the Centers
for Disease Control and Prevention and several state health departments and universities …