The quaternary ammonium salts of chitosan are water soluble derivatives which keep the
promise for real life applications in a large realm of biomedical fields, such as antimicrobial …

Therapeutic peptides/proteins and protein-based antigens are chemically and structurally
labile compounds, which are almost exclusively administered by parenteral injections …

Purpose The purpose of this paper is to present an overview of functional properties of the
polysaccharide-based component and their application in developing edible film and …

Chitosan, a polymer obtained by deacetylation of chitin is widely studied for its
pharmaceutical and nonpharmaceutical applications. Recommendations about uses of this …

Abstract N, N, N-trimethyl chitosan (TMC), a quaternized hydrophilic derivative of chitosan
(CHT), outperformed the well-known solubility issues raised by CHT. The excellent …

Immunotherapy methods using potential tumor microenvironment modulators have elicited
durable therapeutic responses in cancer treatment. Immune checkpoint molecule …

The three water-soluble chitosan derivatives bearing double functional groups were
synthesized with 2, 3-epoxypropyltrimethylammonium chloride and benzaldehyde as …

Chemical modification of chitosan by introducing quaternary ammonium moieties into the
polymer backbone renders excellent antimicrobial activity to the adducts. In the present …

Abstract Induction of Hypoxia Inducible Factor (HIF) as a direct consequence of oxygen
deficiency in tumor tissues is a potent stimulus of CD73 (ecto-5′-nucleotidase) expression …

N-trimethyl chitosan of two quaternization degrees, DQ= 20 and 80mol% and labeled as
TMC20 and TMC80, were synthesized and characterized by 1H NMR. Polyelectrolyte …