The role of DSC MR perfusion in predicting IDH mutation and 1p19q codeletion status in gliomas: meta-analysis and technical considerations

L Siakallis, CC Topriceanu, J Panovska-Griffiths… - Neuroradiology, 2023 - Springer
Purpose Isocitrate dehydrogenase (IDH) mutation and 1p19q codeletion status are
important for managing glioma patients. However, current practice dictates invasive tissue …

Impact of signal intensity normalization of MRI on the generalizability of radiomic-based prediction of molecular glioma subtypes

M Foltyn-Dumitru, M Schell, A Rastogi, F Sahm… - European …, 2024 - Springer
Objectives Radiomic features have demonstrated encouraging results for non-invasive
detection of molecular biomarkers, but the lack of guidelines for pre-processing MRI-data …

Hemodynamic Imaging in Cerebral Diffuse Glioma—Part B: Molecular Correlates, Treatment Effect Monitoring, Prognosis, and Future Directions

V Stumpo, L Guida, J Bellomo, CHB Van Niftrik… - Cancers, 2022 - mdpi.com
Simple Summary Cerebral diffuse gliomas present peculiar molecular features tightly linked
to phenotypic characteristics that are not readily appreciated by means of standard …

Improved performance of non-preloaded and high flip-angle dynamic susceptibility contrast perfusion-weighted imaging sequences in the presurgical differentiation of …

F Wang, X Zhou, R Chen, J Kang, X Yang, J Lin… - European …, 2023 - Springer
Objective This study aimed to compare the accuracy of relative cerebral blood volume
(rCBV) and percentage signal recovery (PSR) obtained from high flip-angle dynamic …

Differentiating IDH-mutant astrocytomas and 1p19q-codeleted oligodendrogliomas using DSC-PWI: high performance through cerebral blood volume and percentage …

A Pons-Escoda, A Garcia-Ruiz, P Naval-Baudin… - European …, 2024 - Springer
Objective Presurgical differentiation between astrocytomas and oligodendrogliomas
remains an unresolved challenge in neuro-oncology. This research aims to provide a …

MR fingerprinting—A radiogenomic marker for diffuse gliomas

E Springer, PL Cardoso, B Strasser, W Bogner… - Cancers, 2022 - mdpi.com
Simple Summary MR imaging of brain tumors is still mainly based on contrast images and 2
quantitative parameters (relative Cerebral Blood Volume and Apparent Diffusion …

Radiomic study on preoperative multi‐modal magnetic resonance images identifies IDH‐mutant TERT promoter‐mutant gliomas

H Wang, S Zhang, X Xing, Q Yue, W Feng… - Cancer …, 2023 - Wiley Online Library
Objectives Gliomas with comutations of isocitrate dehydrogenase (IDH) genes and
telomerase reverse transcriptase (TERT) gene promoter (IDHmut pTERTmut) show distinct …

Completely non-invasive prediction of IDH mutation status based on preoperative native CT images

M Musigmann, M Bilgin, SS Bilgin, H Krähling… - Scientific Reports, 2024 - nature.com
The isocitrate dehydrogenase (IDH) mutation status is one of the most important markers
according to the 2021 WHO classification of CNS tumors. Preoperatively, this information is …

Advancements in Image-Based Models for High-Grade Gliomas Might Be Accelerated

G Frosina - Cancers, 2024 - mdpi.com
Simple Summary We review recent advances in imaging techniques and applications of
artificial intelligence to improve the diagnosis and prognosis of high-grade gliomas, the …

DSC-PWI presurgical differentiation of grade 4 astrocytoma and glioblastoma in young adults: rCBV percentile analysis across enhancing and non-enhancing regions

A Pons-Escoda, P Naval-Baudin, M Viveros… - Neuroradiology, 2024 - Springer
Purpose The presurgical discrimination of IDH-mutant astrocytoma grade 4 from IDH-
wildtype glioblastoma is crucial for patient management, especially in younger adults, aiding …