Post-stroke depression (PSD) is a biopsychosocial disorder that affects individuals who
have suffered a stroke at any point. PSD has a 20 to 60 percent reported prevalence among …

Glutamate's role as a neurotransmitter at synapses has been known for 40 years, but
glutamate has since been shown to regulate neurogenesis, neurite outgrowth …

Glutamate is the primary excitatory neurotransmitter in the mammalian brain. Glutamatergic
neurotransmission may be modulated at multiple levels, only a minority of which are …

Major depression is a debilitating and recurrent disorder with a substantial lifetime risk and a
high social cost. Depressed patients generally display co-morbid symptoms, and depression …

Major depressive disorder (MDD) is a common, chronic, recurrent mental illness that affects
millions of individuals worldwide. To date, the monoaminergic systems (serotonin …

The goal of this study was to evaluate the utility of using plasma levels of amino acids as an
indicator of the severity of depression. The samples were collected from 23 depressed …

Depressive disorders are among the most common psychiatric conditions and contribute to
significant morbidity. Even though the use of antidepressants revolutionized the …

Tianeptine is a clinically used antidepressant that has drawn much attention, because this
compound challenges traditional monoaminergic hypotheses of depression. It is now …

Depression is a highly debilitating disorder that has been estimated to affect up to 21% of
the world population. Despite the advances in the treatment of depression with selective …

Although current models of hippocampal function stress its well-known role in cognitive
functions, historically it has also been viewed as a neural mediator of emotion. Here, we …