The increase in cancer cases is undoubtedly affecting the development of new therapeutic
approaches. Polymeric nanoparticles are of great interest. Due to their relatively small size …

Canonical phototherapeutics have several limitations, including a lack of tumor selectivity,
nondiscriminatory phototoxicity, and tumor hypoxia aggravation. The tumor …

The mitochondrial SIRT3 modulates several biological pathways such as cancer,
metabolism, and hypoxia-related diseases. Recently, we discovered new 1, 4 …

The tumor microenvironment demonstrates great immunophenotypic heterogeneity, which
has been leveraged in traditional immune-hot/cold tumor categorization based on the …

Insulin-like Growth Factor-1 (IGF-1) is a crucial mitogenic factor with important functions in
the mammary gland, mainly through its interaction with the IGF-1 receptor (IGF-1R). This …

Cancer treatment demands innovative approaches. Azithromycin (AZM), traditionally an
antibiotic, shows promise in inhibiting cancer growth due to its anti-inflammatory and …

Cancer, a complex global health burden, necessitates the development of innovative
therapeutic strategies. While chemotherapy remains the primary treatment approach, its …

Gliomas are the most common primary malignant tumors in the central nervous system.
However, conventional treatments, such as surgical resection and postoperative combined …

Epithelial-mesenchymal transition (EMT) is a process in which an epithelial cell undergoes
multiple modifications, acquiring both morphological and functional characteristics of a …

Background It has been reported that the human family with sequence similarity 198,
member B (Fam198b) play an important role in the occurrence and development of various …