Tremendous biomedical advancements in HIV prevention and treatment have led to
aspirational efforts to end the HIV epidemic. However, this goal will not be achieved without …

Background The risk of sexual transmission of HIV from individuals with low-level HIV
viraemia receiving antiretroviral therapy (ART) has important public health implications …

Background The level of evidence for HIV transmission risk through condomless sex in
serodifferent gay couples with the HIV-positive partner taking virally suppressive …

Advances in antiretroviral therapy (ART) have made it possible for persons with human
immunodeficiency virus (HIV) to live a near expected life span, without progressing to AIDS …

The primary national HIV prevention goal is to reduce the annual number of HIV infections
[1]. A key objective to reaching this goal is to increase the percentage of persons living with …

Importance Antiretroviral therapy (ART) is the cornerstone of prevention and management of
HIV infection. Objective To evaluate new data and treatments and incorporate this …

Background An interim analysis of data from the HIV Prevention Trials Network (HPTN) 052
trial showed that antiretroviral therapy (ART) prevented more than 96% of genetically linked …

Background Evidence on viral load and HIV transmission risk in HIV-serodiscordant male
homosexual couples is limited to one published study. We calculated transmission rates in …

Background A universal testing and treatment strategy is a potential approach to reduce the
incidence of human immunodeficiency virus (HIV) infection, yet previous trial results are …

Importance An estimated 1.2 million persons in the US currently have HIV, and more than
760 000 persons have died of complications related to HIV since the first cases were …