Role of cytokines and inflammation in heart function during health and disease

M Bartekova, J Radosinska, M Jelemensky… - Heart failure …, 2018 - Springer
By virtue of their actions on NF-κB, an inflammatory nuclear transcription factor, various
cytokines have been documented to play important regulatory roles in determining cardiac …

[HTML][HTML] Bile acid nuclear receptor FXR and digestive system diseases

L Ding, L Yang, Z Wang, W Huang - Acta Pharmaceutica Sinica B, 2015 - Elsevier
Bile acids (BAs) are not only digestive surfactants but also important cell signaling
molecules, which stimulate several signaling pathways to regulate some important …

Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor

T Inagaki, A Moschetta, YK Lee… - Proceedings of the …, 2006 - National Acad Sciences
Obstruction of bile flow results in bacterial proliferation and mucosal injury in the small
intestine that can lead to the translocation of bacteria across the epithelial barrier and …

Link between chronic inflammation and human papillomavirus-induced carcinogenesis

JV Fernandes… - Oncology …, 2015 - spandidos-publications.com
Inflammation is a defense strategy against invading agents and harmful molecules that is
activated immediately following a stimulus, and involves the release of cytokines and …

Shigella flexneri infection: pathogenesis and vaccine development

AV Jennison, NK Verma - FEMS microbiology reviews, 2004 - academic.oup.com
Shigella flexneri is a gram-negative bacterium which causes the most communicable of
bacterial dysenteries, shigellosis. Shigellosis causes 1.1 million deaths and over 164 million …

Analysis of chicken cytokine and chemokine gene expression following Eimeria acervulina and Eimeria tenella infections

YH Hong, HS Lillehoj, SH Lee, RA Dalloul… - Veterinary immunology …, 2006 - Elsevier
The expression levels of mRNA encoding a panel of 28 chicken cytokines and chemokines
were quantified in intestinal lymphocytes following Eimeria acervulina and Eimeria tenella …

[HTML][HTML] Altered immune system in frailty: genetics and diet may influence inflammation

O Pansarasa, C Pistono, A Davin, M Bordoni… - Ageing research …, 2019 - Elsevier
Frailty is a complex geriatric syndrome associated with biological vulnerability to stressors
and decreased physiological reserve. Its etiology and pathogenesis are not completely …

Caspase-1-Mediated Activation of Interleukin-1β (IL-1β) and IL-18 Contributes to Innate Immune Defenses against Salmonella enterica Serovar Typhimurium …

B Raupach, SK Peuschel, DM Monack… - Infection and …, 2006 - Am Soc Microbiol
ABSTRACT Caspase-1 (Casp-1) mediates the processing of the proinflammatory cytokines
interleukin-1β (IL-1β) and IL-18 to their mature forms. Casp-1-deficient mice succumb more …

Cytokine gene expression profiles during initiation, progression and resolution of periodontitis

JL Ebersole, S Kirakodu, MJ Novak… - Journal of clinical …, 2014 - Wiley Online Library
Aim Variations in the expression of cytokines during the progression of periodontitis remain
ill‐defined. We evaluated the expression of 19 cytokine genes related to T‐cell …

Interleukin‐1 β, interleukin‐12 and interleukin‐18 levels in gingival fluid and serum of patients with gingivitis and periodontitis

A Orozco, E Gemmell, M Bickel… - Oral microbiology and …, 2006 - Wiley Online Library
Introduction: Cytokines are of major importance in periodontal disease progression.
Interleukin‐12 (IL‐12) stimulates interferon‐γ production by T helper type 1 (Th1) cells while …