Impact and prevention of severe exacerbations of COPD: a review of the evidence

DMG Halpin, M Miravitlles, N Metzdorf… - International journal of …, 2017 - Taylor & Francis
Severe exacerbations of COPD, ie, those leading to hospitalization, have profound clinical
implications for patients and significant economic consequences for society. The prevalence …

Risk-to-benefit ratio of inhaled corticosteroids in patients with COPD

D Price, B Yawn, G Brusselle, A Rossi - Primary Care Respiratory …, 2013 - nature.com
While the pharmacological management of chronic obstructive pulmonary disease (COPD)
has evolved from the drugs used to treat asthma, the treatment models are different and the …

Effect of β blockers in treatment of chronic obstructive pulmonary disease: a retrospective cohort study

PM Short, SIW Lipworth, DHJ Elder, S Schembri… - Bmj, 2011 - bmj.com
Objective To examine the effect of β blockers in the management of chronic obstructive
pulmonary disease (COPD), assessing their effect on mortality, hospital admissions, and …

Long‐acting inhaled therapy (beta‐agonists, anticholinergics and steroids) for COPD: a network meta‐analysis

KM Kew, S Dias, CJ Cates - Cochrane Database of Systematic …, 2014 - cochranelibrary.com
Long‐acting inhaled therapy (beta‐agonists, anticholinergics and steroids) for COPD: a
network meta‐analysis - Kew, KM - 2014 | Cochrane Library Skip to Content Cookies Our site …

Inhaled corticosteroids and the risk of pneumonia in people with asthma: a case-control study

T McKeever, TW Harrison, R Hubbard, D Shaw - Chest, 2013 - Elsevier
Background In clinical trials, the use of inhaled corticosteroids is associated with an
increased risk of pneumonia in people with COPD, but whether the same is true for people …

Comparative safety of inhaled medications in patients with chronic obstructive pulmonary disease: systematic review and mixed treatment comparison meta-analysis …

YH Dong, HH Lin, WY Shau, YC Wu, CH Chang… - Thorax, 2013 - thorax.bmj.com
Background The active-treatment comparative safety information for all inhaled medications
in patients with chronic obstructive pulmonary disease (COPD) is limited. We aimed to …

Cardiovascular safety in patients receiving roflumilast for the treatment of COPD

WB White, GE Cooke, PR Kowey, PMA Calverley… - Chest, 2013 - Elsevier
Background Evaluation of cardiovascular safety for new therapies for COPD is important
because of a high prevalence of cardiac comorbidities in the COPD population. Hence, we …

Risk of pneumonia associated with long-term use of inhaled corticosteroids in chronic obstructive pulmonary disease: a critical review and update

S Singh, YK Loke - Current opinion in pulmonary medicine, 2010 - journals.lww.com
Clinicians should consider the long-term risks of pneumonia with the use of inhaled
corticosteroids in patients with COPD. Adequately powered long-term head-to-head trials …

Inhaled corticosteroids versus long‐acting beta2‐agonists for chronic obstructive pulmonary disease

S Spencer, C Karner, CJ Cates… - Cochrane Database of …, 2011 - cochranelibrary.com
Background Long‐acting beta 2‐agonists and inhaled corticosteroids can be used as
maintenance therapy by patients with moderate to severe chronic obstructive pulmonary …

Real-world evidence: bridging gaps in evidence to guide payer decisions

MH Roberts, GT Ferguson - PharmacoEconomics-Open, 2021 - Springer
Randomized controlled trials (RCTs) are preferred by payers for health technology
assessments and coverage decisions. However, the inclusion of a highly selective patient …