The gut‐associated lymphoid tissue is the largest immune organ in the body and is the
primary route by which we are exposed to antigens. Tolerance induction is the default …

The primary design of this perspective is to describe the major ligand classes of the aryl
hydrocarbon receptor (AHR). A grander objective is to provide models that may help define …

The ligand-activated transcription factor aryl hydrocarbon receptor (AHR) participates in the
differentiation of FoxP3+ Treg, Tr1 cells, and IL-17–producing T cells (Th17). Most of our …

Multiple mechanisms of tolerance are induced by oral antigen. Low doses favor active
suppression, whereas higher doses favor clonal anergy/deletion. Oral antigen induces T …

When looking for a book on fish toxicology, you might find one that discusses the
biochemical and molecular aspects, or one that focuses aquatic toxicology in general. You …

The aryl hydrocarbon receptor (AHR) is a protein best known for its role in mediating toxicity.
Over 30 years of research has uncovered additional roles for the AHR in xenobiotic …

Aryl hydrocarbon receptor (AhR) is an important transcriptional regulator of drug
metabolizing enzymes that dominantly controls the expression of cytochrome P450 CYP1 …

The aryl hydrocarbon receptor (AHR) is a member of the basic helix-loop-helix/Per-ARNT-
Sim (bHLH-PAS) family of transcription factors and has broad biological functions. Early after …

The science of toxicology is devoted, in large part, to understanding mechanisms of toxicity
so that we can more accurately assess the risk posed by exposure to xenobiotic agents and …

The aryl hydrocarbon receptor (AhR) belongs to the essential helix-loop-helix transcription
factors family. This receptor has a central role in determining host physiology and a variety of …