Growth and division of the peptidoglycan matrix

PDA Rohs, TG Bernhardt - Annual review of microbiology, 2021 - annualreviews.org
Most bacteria are surrounded by a peptidoglycan cell wall that defines their shape and
protects them from osmotic lysis. The expansion and division of this structure therefore plays …

Fundamental principles in bacterial physiology—history, recent progress, and the future with focus on cell size control: a review

S Jun, F Si, R Pugatch, M Scott - Reports on Progress in Physics, 2018 - iopscience.iop.org
Bacterial physiology is a branch of biology that aims to understand overarching principles of
cellular reproduction. Many important issues in bacterial physiology are inherently …

Pulmonary delivery nanomedicines towards circumventing physiological barriers: Strategies and characterization approaches

W Wang, Z Huang, Y Huang, X Zhang, J Huang… - Advanced Drug Delivery …, 2022 - Elsevier
Pulmonary delivery of nanomedicines is very promising in lung local disease treatments
whereas several physiological barriers limit its application via the interaction with inhaled …

A central role for PBP2 in the activation of peptidoglycan polymerization by the bacterial cell elongation machinery

PDA Rohs, J Buss, SI Sim, GR Squyres… - PLoS …, 2018 - journals.plos.org
Cell elongation in rod-shaped bacteria is mediated by the Rod system, a conserved
morphogenic complex that spatially controls cell wall assembly by the glycan polymerase …

Bacillus subtilis cell diameter is determined by the opposing actions of two distinct cell wall synthetic systems

MF Dion, M Kapoor, Y Sun, S Wilson, J Ryan… - Nature …, 2019 - nature.com
Rod-shaped bacteria grow by adding material into their cell wall via the action of two
spatially distinct enzymatic systems: the Rod complex moves around the cell circumference …

Growth rate is modulated by monitoring cell wall precursors in Bacillus subtilis

Y Sun, S Hürlimann, E Garner - Nature Microbiology, 2023 - nature.com
How bacteria link their growth rate to external nutrient conditions is unknown. To investigate
how Bacillus subtilis cells alter the rate at which they expand their cell walls as they grow …

Antibiotic resistance via bacterial cell shape-shifting

N Ojkic, D Serbanescu, S Banerjee - Mbio, 2022 - Am Soc Microbiol
Bacteria have evolved to develop multiple strategies for antibiotic resistance by effectively
reducing intracellular antibiotic concentrations or antibiotic binding affinities, but the role of …

Prokaryotic cytoskeletons: protein filaments organizing small cells

J Wagstaff, J Löwe - Nature Reviews Microbiology, 2018 - nature.com
Most, if not all, bacterial and archaeal cells contain at least one protein filament system.
Although these filament systems in some cases form structures that are very similar to …

Don't let sleeping dogmas lie: new views of peptidoglycan synthesis and its regulation

H Zhao, V Patel, JD Helmann, T Dörr - Molecular microbiology, 2017 - Wiley Online Library
Bacterial cell wall synthesis is the target for some of our most powerful antibiotics and has
thus been the subject of intense research focus for more than 50 years. Surprisingly, we still …

A unifying autocatalytic network-based framework for bacterial growth laws

A Roy, D Goberman, R Pugatch - Proceedings of the …, 2021 - National Acad Sciences
Recently discovered simple quantitative relations, known as bacterial growth laws, hint at
the existence of simple underlying principles at the heart of bacterial growth. In this work, we …