The causative agent of human tuberculosis, Mycobacterium tuberculosis complex (MTBC), comprises seven phylogenetically distinct lineages associated with different geographical …
D Brites, S Gagneux - Immunological reviews, 2015 - Wiley Online Library
The causative agent of human tuberculosis (TB), M ycobacterium tuberculosis, is an obligate pathogen that evolved to exclusively persist in human populations. For M. tuberculosis to …
Q Wang, HIM Boshoff, JR Harrison, PC Ray, SR Green… - Science, 2020 - science.org
Mycobacterium tuberculosis has an unusual outer membrane that lacks canonical porin proteins for the transport of small solutes to the periplasm. We discovered that 3, 3-bis-di …
The pe/ppe genes represent one of the most intriguing aspects of the M ycobacterium tuberculosis genome. These genes are especially abundant in pathogenic mycobacteria …
With the continued increase of genomic information and computational analyses during the recent years, the number of newly discovered calcium binding proteins (CaBPs) in …
T Jagielski, A Minias, J van Ingen… - Clinical microbiology …, 2016 - Am Soc Microbiol
Molecular typing has revolutionized epidemiological studies of infectious diseases, including those of a mycobacterial etiology. With the advent of fingerprinting techniques …
Q Chai, X Wang, L Qiang, Y Zhang, P Ge, Z Lu… - Nature …, 2019 - nature.com
Ubiquitin-mediated xenophagy, a type of selective autophagy, plays crucial roles in host defense against intracellular pathogens including Mycobacterium tuberculosis (Mtb) …
Suppression of major histocompatibility complex (MHC) class II antigen presentation is believed to be among the major mechanisms used by Mycobacterium tuberculosis to …
LS Ates - Molecular microbiology, 2020 - Wiley Online Library
The PE and PPE proteins of Mycobacterium tuberculosis have been studied with great interest since their discovery. Named after the conserved proline (P) and glutamic acid (E) …