This article provides an overview of studies addressing effects of ionizing radiation on the
heart. Clinical studies have identified early and late manifestations of radiation-induced …

Future long-distance space missions will be associated with significant exposures to
ionizing radiation, and the health risks of these radiation exposures during manned missions …

DNA methylation is a key epigenetic mechanism, needed for proper control over the
expression of genetic information and silencing of repetitive elements. Exposure to ionizing …

There is an ongoing shift in demographics such that older persons will outnumber young
persons in the coming years, and with it age-associated tissue attrition and increased …

Purpose: Recent evidence suggests that the heart may be injured by ionizing radiation at
lower doses than was previously thought. This raises concerns about the cardiovascular …

Updated measurements of charged particle fluxes during the transit from Earth to Mars as
well as on site measurements by Curiosity of Martian surface radiation fluxes identified …

Purpose: Astronauts in space vehicles beyond low-Earth orbit will be exposed to high
charge and energy (HZE) ions, and there is concern about potential adverse effects on the …

Background A manned mission to Mars has been contemplated by the world's largest space
agencies for a number of years. The duration of the trip would necessitate a much longer …

Missions into deep space will expose astronauts to the harsh space environment, and the
degenerative tissue effects of space radiation are largely unknown. To assess the risks, in …

In recent times, space flights receive continued interest. Humankind's next two goals are to
return to the Moon and, a few years later, to land on the surface of Mars. Although …