Traumatic brain injury (TBI) causes secondary biochemical changes that contribute to
subsequent tissue damage and associated neuronal cell death. Neuroprotective treatments …

Significance: A vast amount of circumstantial evidence implicates high energy oxidants and
oxidative stress as mediators of secondary damage associated with traumatic brain injury …

Late-onset sporadic Alzheimer's disease is a heterogeneous disorder. In elderly patients,
increasing evidence suggests a link between this neurodegenerative disease, and vascular …

Traumatic brain injury (TBI) remains a major public health problem globally. Presently, there
is no way to restore cognitive deficits caused by TBI. In this study, we seek to evaluate the …

Vascular dementia (VaD) is an etiologic category that includes clinical forms of dementia
caused by ischemic or hemorrhagic cerebrovascular disease (CVD) or by ischemic-hypoxic …

Parkinson's disease (PD) is second only to Alzheimer's disease as the most common
devastating human neurodegenerative disorder. Despite intense investigation, no …

Traumatic brain injury (TBI) remains one of the leading causes of mortality and morbidity
worldwide in individuals under the age of 45 years, and, despite extensive efforts to develop …

Background Trial and observational evidence is conflicting in terms of the association of
blood lipids, atherosclerosis and statin use with dementia and cognitive impairment in the …

Traumatic brain injury (TBI) is a major cause of mortality and morbidity worldwide. Despite
extensive preclinical research supporting the effectiveness of neuroprotective therapies for …

Purpose.: To validate an established adult organotypic retinal explant culture system for use
as an efficient medium-throughput screening tool to investigate novel retinal ganglion cell …