Diagnosis and treatment of primary aldosteronism

M Reincke, I Bancos, P Mulatero, UI Scholl… - The lancet Diabetes & …, 2021 - thelancet.com
Primary aldosteronism is a common cause of secondary hypertension associated with
excess cardiovascular morbidities. Primary aldosteronism is underdiagnosed because it …

[HTML][HTML] Overview of the 2022 WHO classification of adrenal cortical tumors

O Mete, LA Erickson, CC Juhlin, RR de Krijger… - Endocrine …, 2022 - Springer
The new WHO classification of adrenal cortical proliferations reflects translational advances
in the fields of endocrine pathology, oncology and molecular biology. By adopting a …

The unrecognized prevalence of primary aldosteronism: a cross-sectional study

JM Brown, M Siddiqui, DA Calhoun… - Annals of Internal …, 2020 - acpjournals.org
Background: Primary aldosteronism is a nonsuppressible renin-independent aldosterone
production that causes hypertension and cardiovascular disease. Objective: To characterize …

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

E Evangelou, HR Warren, D Mosen-Ansorena… - Nature …, 2018 - nature.com
High blood pressure is a highly heritable and modifiable risk factor for cardiovascular
disease. We report the largest genetic association study of blood pressure traits (systolic …

Cardiovascular events and target organ damage in primary aldosteronism compared with essential hypertension: a systematic review and meta-analysis

S Monticone, F D'Ascenzo, C Moretti… - The lancet Diabetes & …, 2018 - thelancet.com
Background There is conflicting evidence, relying on heterogeneous studies, as to whether
aldosterone excess is responsible for an increased risk of cardiovascular and …

The management of primary aldosteronism: case detection, diagnosis, and treatment: an endocrine society clinical practice guideline

JW Funder, RM Carey, F Mantero… - The Journal of …, 2016 - academic.oup.com
Objective: To develop clinical practice guidelines for the management of patients with
primary aldosteronism. Participants: The Task Force included a chair, selected by the …

Genetics, prevalence, screening and confirmation of primary aldosteronism: a position statement and consensus of the working group on endocrine hypertension of …

P Mulatero, S Monticone, J Deinum, L Amar… - Journal of …, 2020 - journals.lww.com
Autonomous aldosterone overproduction represents the underlying condition of 5–10% of
patients with arterial hypertension and carries a significant burden of mortality and morbidity …

[HTML][HTML] Potassium homeostasis and management of dyskalemia in kidney diseases: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) …

CM Clase, JJ Carrero, DH Ellison, ME Grams… - Kidney international, 2020 - Elsevier
Potassium disorders are common in patients with kidney disease, particularly in patients
with tubular disorders and low glomerular filtration rate. A multidisciplinary group of …

Adrenal incidentaloma

M Sherlock, A Scarsbrook, A Abbas, S Fraser… - Endocrine …, 2020 - academic.oup.com
An adrenal incidentaloma is now established as a common endocrine diagnosis that
requires a multidisciplinary approach for effective management. The majority of patients can …

Diagnosis and treatment of primary aldosteronism: practical clinical perspectives

WF Young Jr - Journal of internal medicine, 2019 - Wiley Online Library
Primary aldosteronism (PA), the most common form of secondary hypertension, can be
either surgically cured or treated with targeted pharmacotherapy. PA is frequently …