Application of magnetic nanoparticles in nucleic acid detection

C Tang, Z He, H Liu, Y Xu, H Huang, G Yang… - Journal of …, 2020 - Springer
Nucleic acid is the main material for storing, copying, and transmitting genetic information.
Gene sequencing is of great significance in DNA damage research, gene therapy, mutation …

Long noncoding RNA and cancer: a new paradigm

A Bhan, M Soleimani, SS Mandal - Cancer research, 2017 - AACR
In addition to mutations or aberrant expression in the protein-coding genes, mutations and
misregulation of noncoding RNAs, in particular long noncoding RNAs (lncRNA), appear to …

Long non-coding RNAs regulate drug resistance in cancer

K Liu, L Gao, X Ma, JJ Huang, J Chen, L Zeng… - Molecular cancer, 2020 - Springer
Chemoresistance, whether intrinsic or acquired, is a major obstacle in the treatment of
cancer. The resistance of cancer cells to chemotherapeutic drugs can result from various …

Crosstalk between calcium and reactive oxygen species signaling in cancer

N Hempel, M Trebak - Cell calcium, 2017 - Elsevier
The interplay between Ca 2+ and reactive oxygen species (ROS) signaling pathways is well
established, with reciprocal regulation occurring at a number of subcellular locations. Many …

[HTML][HTML] LncRNA SNHG6 is associated with poor prognosis of gastric cancer and promotes cell proliferation and EMT through epigenetically silencing p27 and …

K Yan, J Tian, W Shi, H Xia, Y Zhu - Cellular Physiology and …, 2017 - karger.com
Background/Amis: Long non-coding RNAs (lncRNAs), a novel class of transcripts, have
been shown to play critical roles in diverse cellular biological processes, including …

[HTML][HTML] Ion channels in the regulation of apoptosis

A Kondratskyi, K Kondratska, R Skryma… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Apoptosis, a type of genetically controlled cell death, is a fundamental cellular mechanism
utilized by multicellular organisms for disposal of cells that are no longer needed or …

Long non‐coding RNAs in cancer: another layer of complexity

JC de Oliveira, LC Oliveira, C Mathias… - The journal of gene …, 2019 - Wiley Online Library
We review the most well characterized long non‐coding RNAs (lncRNAs) with important
roles in hallmarks of cancer, additionally including lncRNAs with a higher potential for …

Long noncoding RNA TRPM2-AS acts as a microRNA sponge of miR-612 to promote gastric cancer progression and radioresistance

J Xiao, L Lin, D Luo, L Shi, W Chen, H Fan, Z Li, X Ma… - Oncogenesis, 2020 - nature.com
Long noncoding RNAs (lncRNAs) are emerging as important regulators of tumorigenesis
and are frequently dysregulated in cancers. Here, we identify a critical lncRNA TRPM2-AS …

Long non‐coding RNAs and prostate cancer

A Misawa, K Takayama, S Inoue - Cancer science, 2017 - Wiley Online Library
Long non‐coding RNAs (lncRNAs) are RNA transcripts larger than 200 nucleotides that do
not code for proteins the aberrant expression of which has been documented in various …

Long non-coding RNAs in genitourinary malignancies: a whole new world

R Flippot, G Beinse, A Boilève, J Vibert… - Nature Reviews …, 2019 - nature.com
Long non-coding RNAs (lncRNAs) are regulators of cellular machinery that are commonly
dysregulated in genitourinary malignancies. Accordingly, the investigation of lncRNAs is …