The pinacol rearrangement1 is a well-known reaction. It refers to the acid-catalyzed
transformation of 1, 2-diols to ketones or aldehydes by 1, 2-migration of a CÀC or CÀH bond …

We review here the methods by which a silyl group, incorporated into an organic structure,
has been used in organic synthesis to control stereochemistry, or has been an integral but …

Organic chemistry is not a pure science, despite claims to the contrary. However, neither is it
stagnating nor is it in decline. Instead, it is turning its attention to ever more challenging …

Allylsilanes and vinylsilanes usually react with electrophiles to give substitution. These
reactions are conveniently understood as the reactions of alkenes that have been …

The normal reactivity of a carbonyl compound (I) is as an a 1-reagent (II) and the temporary
reversal of the characteristic pattern of reactivity of a functional group is described by the …

The use of dimethyl sulfoxide as an oxidizing agent began with the discoveries by Kornblum
and co‐workers that certain α‐bromo ketones were converted into glyoxals under mild …

Reduction of aldehydes and ketones with hydrosilanes proceeded in the presence of a
catalytic amount of tetrabutylammonium fluoride or tris (diethylamino) sulfonium …

Es wird der Versuch unternommen, wichtige Entwicklungen auf dem Gebiet der
Organischen Synthese in den letzten 25 Jahren zu skizzieren und in die Zukunft zu …

Sequences of directly adjacent stereogenic centers were first discovered for the
monosaccharides, which therefore constituted the first focus of interest in Stereoselective …

Asymmetrische Pinakolumlagerung: Die Pinakolumlagerung gilt seit langem als schwer
kontrollierbar im Hinblick auf Regio‐und Stereoselektivität. Nun wurde gefunden, dass …