Physics and biology of ultrahigh dose-rate (FLASH) radiotherapy: a topical review

N Esplen, MS Mendonca… - Physics in Medicine & …, 2020 - iopscience.iop.org
Ultrahigh dose-rate radiotherapy (RT), or'FLASH'therapy, has gained significant momentum
following various in vivo studies published since 2014 which have demonstrated a reduction …

Advances in kilovoltage x-ray beam dosimetry

R Hill, B Healy, L Holloway, Z Kuncic… - Physics in Medicine …, 2014 - iopscience.iop.org
This topical review provides an up-to-date overview of the theoretical and practical aspects
of therapeutic kilovoltage x-ray beam dosimetry. Kilovoltage x-ray beams have the property …

[HTML][HTML] Medical physics aspects of the synchrotron radiation therapies: Microbeam radiation therapy (MRT) and synchrotron stereotactic radiotherapy (SSRT)

E Bräuer-Krisch, JF Adam, E Alagoz, S Bartzsch… - Physica Medica, 2015 - Elsevier
Abstract Stereotactic Synchrotron Radiotherapy (SSRT) and Microbeam Radiation Therapy
(MRT) are both novel approaches to treat brain tumor and potentially other tumors using …

Transforming an IORT linac into a FLASH research machine: procedure and dosimetric characterization

G Felici, P Barca, S Barone, E Bortoli… - Frontiers in …, 2020 - frontiersin.org
Since Favaudon's paper of 2014, there has been an increasing interest in FLASH
radiotherapy. The FLASH modality could represent a breakthrough in radiation oncology; …

Gafchromic EBT3 film dosimetry in electron beams—energy dependence and improved film read‐out

P Sipilä, J Ojala, S Kaijaluoto… - Journal of applied …, 2016 - Wiley Online Library
For megavoltage photon radiation, the fundamental dosimetry characteristics of Gafchromic
EBT3 film were determined in gamma ray beam with addition of experimental and Monte …

Dosimetric characterization of a novel UHDR megavoltage X-ray source for FLASH radiobiological experiments

N Esplen, L Egoriti, T Planche, S Rädel, HW Koay… - Scientific Reports, 2024 - nature.com
A first irradiation platform capable of delivering 10 MV X-ray beams at ultra-high dose rates
(UHDR) has been developed and characterized for FLASH radiobiological research at …

Experimental investigation of GafChromic® EBT3 intrinsic energy dependence with kilovoltage x rays, 137Cs, and 60Co

CG Hammer, BS Rosen, JM Fagerstrom… - Medical …, 2018 - Wiley Online Library
Purpose To determine experimentally the intrinsic energy response, kbq, of EBT3
GafChromic® radiochromic film with kilovoltage x rays, 137Cs, and 60Co in therapeutic and …

Dose delivery uncertainties assessment in the field junction region of craniospinal irradiation with Volumetric Modulated Arc Therapy using a robustness index and …

V Peppa, E Zoros, A Alexiou, G Pissakas, P Karaiskos - Plos one, 2024 - journals.plos.org
Due to its inherent technical challenges, craniospinal irradiation (CSI) entails crucial
considerations regarding plan complexity and robustness. The scope of this work was to …

Investigation of EBT 3 radiochromic film's response to humidity

EY León‐Marroquín… - Journal of applied …, 2018 - Wiley Online Library
Purpose The aim of this work is to investigate the effects of immersing EBT 3 radiochromic
film in water and to evaluate its contribution to the total uncertainty in dose determination …

Experimental characterization of magnetically focused electron contamination at the surface of a high‐field inline MRI‐linac

NF Roberts, E Patterson, U Jelen, T Causer… - Medical …, 2019 - Wiley Online Library
Purpose The fringe field of the Australian MRI‐linac causes contaminant electrons to be
focused along the central axis resulting in a high surface dose. This work aims to …